SCHEMBL4389307

SCHEMBL4389307

C=CCc1nccc2ccccc12.[O-][Cl+2]([O-])O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
PLAU P00749 2/20 0.39
CYP2A6 P11509 1/20 0.39
F12 P00748 1/20 0.39
NCF1 P14598 1/20 0.39
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
NOS2 P35228 1/20 0.39
BACE1 P56817 1/20 0.39
PLG P00747 1/20 0.36
CFTR P13569 1/20 0.36
GOPC Q9HD26 1/20 0.36
MAPT P10636 2/20 0.35
HSD17B10 Q99714 1/20 0.35
ACHE P22303 1/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
NCOA3 Q9Y6Q9 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131316 0.91 PLAU (0.46) LMNAPLAUCYP2A6F12NCF1
SCHEMBL29373584 0.91 PLAU (0.46) LMNAPLAUCYP2A6F12NCF1
Bromide SCHEMBL299632 0.89 PLAU (0.44) LMNAPLAUCYP2A6F12NCF1
Hydrochloric Acid SCHEMBL2570754 0.89 PLAU (0.44) LMNAPLAUCYP2A6F12NCF1
Ammonia Solution, Strong SCHEMBL28140044 0.89 PLAU (0.44) LMNAPLAUCYP2A6F12NCF1
Hydrochloric Acid SCHEMBL2222537 0.89 PLAU (0.44) LMNAPLAUCYP2A6F12NCF1
SCHEMBL27879304 0.84 PLAU (0.41) LMNAPLAUCYP2A6F12NCF1
Quinoline SCHEMBL28833127 0.81 ALDH1A1 (0.50) LMNAPLAUCYP2A6F12NCF1
SCHEMBL23886136 0.75 PLAU (0.47) LMNAPLAUCYP2A6F12NCF1
SCHEMBL11349520 0.74 PLAU (0.43) LMNAPLAUCYP2A6F12NCF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8843033-B2 Developer supplier, image forming apparatus, developer supplying method and image forming method RICOH COMPANY, LTD. (JP) 2014-09-23 US disclosed
US-20090180813-A1 Developer supplier, image forming apparatus, developer supplying method and image forming method RICOH COMPANY, LTD. 2009-07-16 US disclosed