SCHEMBL4389370

SCHEMBL4389370

O=C(O)CCCCCCCCCC(=O)C(=O)O

nearest known ligand 0.94

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.71
LMNA P02545 3/20 0.71
NFKB1 P19838 1/20 0.71
PMP22 Q01453 1/20 0.71
OR51E2 Q9H255 2/20 0.63
MAPK1 P28482 1/20 0.63
SLC13A3 Q8WWT9 1/20 0.63
EGLN1 Q9GZT9 1/20 0.63
GPR84 Q9NQS5 8/20 0.57
FFAR1 O14842 2/20 0.57
FFAR4 Q5NUL3 2/20 0.57
SLC22A6 Q4U2R8 2/20 0.56
PPARG P37231 6/20 0.55
PPARD Q03181 6/20 0.55
PPARA Q07869 6/20 0.55
HDAC11 Q96DB2 5/20 0.55
ALDH1A1 P00352 3/20 0.55
TLR2 O60603 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
MEN1 O00255 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2780784 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22OR51E2
SCHEMBL9186388 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22OR51E2
SCHEMBL20537125 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22OR51E2
SCHEMBL2780957 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22OR51E2
SCHEMBL9794734 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22OR51E2
SCHEMBL10592204 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22OR51E2
SCHEMBL2993356 1.00 TSHR (0.71) TSHRLMNANFKB1PMP22OR51E2
SCHEMBL15054423 0.97 TSHR (0.67) TSHRLMNANFKB1PMP22OR51E2
SCHEMBL14357994 0.97 LMNA (0.69) TSHRLMNANFKB1PMP22OR51E2
SCHEMBL259198 0.97 LMNA (0.69) TSHRLMNANFKB1PMP22OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2126021-A1 COMPOSITION AND PROCESS Reckitt Benckiser N.V. (NL) 2009-12-02 EP disclosed
EP-2010638-A1 CLEANING COMPOSITION AND PROCESS Reckitt Benckiser N.V. (NL) 2009-01-07 EP disclosed
EP-2004787-A1 COMPOSITION AND PROCESS Reckitt Benckiser N.V. (NL) 2008-12-24 EP disclosed
EP-1994131-A1 COMPOSITION AND PROCESS Reckitt Benckiser N.V. (NL) 2008-11-26 EP disclosed
EP-1984483-A1 DETERGENT COMPOSITION Reckitt Benckiser N.V. (NL) 2008-10-29 EP disclosed
WO-2008096137-A1 COMPOSITION AND PROCESS RECKITT BENCKISER N.V. (NL) 2008-08-14 WO disclosed
EP-1951856-A1 SOLID CLEANING FORMULATIONS Reckitt Benckiser N.V. (NL) 2008-08-06 EP disclosed
WO-2007119054-A1 COMPOSITION AND PROCESS RECKITT BENCKISER N.V. (NL) 2007-10-25 WO disclosed
WO-2007119053-A1 CLEANING COMPOSITION AND PROCESS RECKITT BENCKISER N.V. (NL) 2007-10-25 WO disclosed
WO-2007104955-A1 COMPOSITION AND PROCESS RECKITT BENCKISER N.V. (NL) 2007-09-20 WO disclosed
EP-1012251-A1 PROTEASE VARIANTS AND COMPOSITIONS NOVO NORDISK A/S (DK) 2000-06-28 EP disclosed
EP-1009815-A1 PROTEASE VARIANTS AND COMPOSITIONS NOVO NORDISK A/S (DK) 2000-06-21 EP disclosed
WO-1999011768-A1 PROTEASE VARIANTS AND COMPOSITIONS NOVO NORDISK A/S (DK) 1999-03-11 WO disclosed
WO-1999011769-A1 PROTEASE VARIANTS AND COMPOSITIONS NOVO NORDISK A/S (DK) 1999-03-11 WO disclosed
EP-0550690-A1 POLYHYDROXY FATTY ACID AMIDE SURFACTANTS IN BLEACH-CONTAINING DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1993-07-14 EP disclosed
EP-0367296-A2 Ether carboxylate detergent builders THE PROCTER & GAMBLE COMPANY (US) 1990-05-09 EP disclosed
US-4689393-A Preparation of block polyetherester amide from carboxy terminated polyamide and dihydroxy polyether with tin compound catalyst EMS-INVENTA A.G. (CH) 1987-08-25 US disclosed
EP-0233010-A2 Detergency builder system THE PROCTER & GAMBLE COMPANY (US) 1987-08-19 EP disclosed
EP-0232114-A2 Ether carboxylate detergent builders and process for their preparation THE PROCTER & GAMBLE COMPANY (US) 1987-08-12 EP disclosed
EP-0192441-A2 Detergency builder system THE PROCTER & GAMBLE COMPANY (US) 1986-08-27 EP disclosed