Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.71 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.63 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.63 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 6/20 | 0.55 |
| ▸ | PPARD | Q03181 | 6/20 | 0.55 |
| ▸ | PPARA | Q07869 | 6/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TLR2 | O60603 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780784 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22OR51E2 | |
| SCHEMBL9186388 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22OR51E2 | |
| SCHEMBL20537125 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22OR51E2 | |
| SCHEMBL9794734 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22OR51E2 | |
| SCHEMBL4389370 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22OR51E2 | |
| SCHEMBL10592204 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22OR51E2 | |
| SCHEMBL2993356 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22OR51E2 | |
| SCHEMBL15054423 | 0.97 | TSHR (0.67) | TSHRLMNANFKB1PMP22OR51E2 | |
| SCHEMBL14357994 | 0.97 | LMNA (0.69) | TSHRLMNANFKB1PMP22OR51E2 | |
| SCHEMBL259198 | 0.97 | LMNA (0.69) | TSHRLMNANFKB1PMP22OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728133-B2 | Stable pharmaceutical compositions | B&G PARTNERS LLC | 2010-06-01 | — | — | US | disclosed |
| US-20050130975-A1 | Stable pharmaceutical compositions | B&G PARTNERS LLC | 2005-06-16 | — | — | US | disclosed |
| US-6825196-B2 | SUCH AS 1-HYDRAZINOPHTHALAZINE; METAL-FREE | BARBEAU PHARMA, INC. | 2004-11-30 | — | — | US | disclosed |
| US-6821974-B2 | VASODILATION; HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS | BARBEAU PHARMA, INC | 2004-11-23 | — | — | US | disclosed |
| US-4622301-A | DISINTEGRATION OF PROTEUS | BASF AKTIENGESELLSCHAFT (DE) | 1986-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130975-A1 | Stable pharmaceutical compositions | CYP3A7, NR1H2, CYP2B6 | TSHR 2122/4885LMNA 2421/4885NFKB1 2428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.