Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.63 |
| ▸ | MME | P08473 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.31 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94787 | 0.91 | AR (0.62) | ARMMEALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL94331 | 0.90 | AR (0.63) | ARMMEALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL94273 | 0.85 | AR (0.58) | ARMMEALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL440793 | 0.83 | AR (0.72) | ARMMEALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL94279 | 0.81 | MME (0.55) | ARMME | |
| SCHEMBL94364 | 0.81 | AR (0.69) | ARMMEALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL95327 | 0.79 | AR (0.63) | ARMME | |
| SCHEMBL95202 | 0.78 | MME (0.55) | ARMMEALDH1A1 | |
| SCHEMBL438874 | 0.77 | AR (0.64) | ARMME | |
| SCHEMBL94639 | 0.77 | AR (0.60) | ARMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065231-A1 | THIOPHENE DERIVATIVE | SUMITOMO CHEMICAL COMPANY LTD. (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065231-A1 | THIOPHENE DERIVATIVE | AR, NR5A1, SHBG | AR 1/4885MME 1367/4885ALDH1A1 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.