Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11326487 | 0.98 | CA2 (0.46) | CA2LMNACTDSP1NR1H2HSP90AA1 | |
| SCHEMBL5382245 | 0.86 | CA2 (0.50) | CA2LMNACTDSP1NR1H2HSP90AA1 | |
| SCHEMBL537146 | 0.86 | LMNA (0.56) | CA2LMNACTDSP1NR1H2HSP90AA1 | |
| SCHEMBL536376 | 0.86 | LMNA (0.51) | CA2LMNACTDSP1NR1H2HSP90AA1 | |
| Hydrochloric Acid SCHEMBL5384426 | 0.84 | CA2 (0.48) | CA2LMNACTDSP1NR1H2HSP90AA1 | |
| SCHEMBL10698165 | 0.84 | LMNA (0.54) | CA2LMNACTDSP1NR1H2HSP90AA1 | |
| SCHEMBL10699634 | 0.84 | LMNA (0.54) | CA2LMNACTDSP1NR1H2HSP90AA1 | |
| SCHEMBL10407904 | 0.81 | NR1H2 (0.55) | CA2LMNACTDSP1NR1H2HSP90AA1 | |
| SCHEMBL3235087 | 0.80 | CA2 (0.56) | CA2LMNACTDSP1NR1H2HSP90AA1 | |
| SCHEMBL26192698 | 0.80 | LMNA (0.47) | CA2LMNACTDSP1NR1H2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572908-B2 | Cleavable linkers for polynucleotides | AGILENT TECHNOLOGIES, INC. (US) | 2009-08-11 | — | — | US | disclosed |
| US-7572908-B2 | Cleavable linkers for polynucleotides | AGILENT TECHNOLOGIES, INC. (US) | 2009-08-11 | — | — | US | disclosed |
| US-7572908-B2 | Cleavable linkers for polynucleotides | AGILENT TECHNOLOGIES, INC. (US) | 2009-08-11 | — | — | US | disclosed |
| WO-2007112264-A2 | CLEAVABLE LINKERS FOR POLYNUCLEOTIDES | AGILENT TECHNOLOGIES, INC. (US) | 2007-10-04 | — | — | WO | disclosed |
| US-20070224603-A1 | Cleavable linkers for polynucleotides | AGILENT TECHNOLOGIES, INC. | 2007-09-27 | — | — | US | disclosed |
| US-20070224603-A1 | Cleavable linkers for polynucleotides | AGILENT TECHNOLOGIES, INC. | 2007-09-27 | — | — | US | disclosed |
| US-20070224603-A1 | Cleavable linkers for polynucleotides | AGILENT TECHNOLOGIES, INC. | 2007-09-27 | — | — | US | disclosed |
| US-6171520-B1 | Reagents for labeling SH groups, process for the preparation of them and method for labeling with them | SS PHARMACEUTICAL CO., LTD. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0844246-A1 | REAGENTS FOR LABELING SH GROUPS, PROCESS FOR THE PREPARATION OF THEM, AND METHOD FOR LABELING WITH THEM | SS Pharmaceutical Co., Ltd. (JP) | 1998-05-27 | — | — | EP | disclosed |
| US-4246201-A | Substituted N-(3-phenylthiopropyl)-3,3-diphenyl-propylamines possessing pharmacological activity | ALFA FARMACEUTICI, S.P.A. (IT) | 1981-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070224603-A1 | Cleavable linkers for polynucleotides | PNKP, PCNA, TYMP | CA2 4010/4885LMNA 133/4885CTDSP1 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.