Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 17/20 | 0.50 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441483 | 0.90 | DGAT1 (0.49) | DGAT1NPC1RAB9AKDM5B | |
| SCHEMBL438989 | 0.86 | DGAT1 (0.51) | DGAT1 | |
| Benzene SCHEMBL436845 | 0.77 | DGAT1 (0.55) | DGAT1KDM5B | |
| SCHEMBL437706 | 0.77 | DGAT1 (0.54) | DGAT1KDM5B | |
| SCHEMBL441010 | 0.77 | DGAT1 (0.46) | DGAT1 | |
| Methane SCHEMBL437966 | 0.76 | DGAT1 (0.54) | DGAT1KDM5B | |
| SCHEMBL440803 | 0.76 | DGAT1 (0.56) | DGAT1 | |
| SCHEMBL14305126 | 0.76 | DGAT1 (0.46) | DGAT1KDM5B | |
| SCHEMBL437998 | 0.75 | DGAT1 (0.62) | DGAT1KDM5B | |
| SCHEMBL441025 | 0.75 | DGAT1 (0.52) | DGAT1KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
| US-20120065196-A1 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | DGAT2, DGAT1, DLAT | DGAT1 2/4885SPR 2972/4885NPC1 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.