SCHEMBL4390436

SCHEMBL4390436

Oc1ccccc1-c1cccc(-c2ccccc2O)c1-c1ccccc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
HPGD P15428 5/20 0.52
HSD17B10 Q99714 5/20 0.52
BCL2L1 Q07817 1/20 0.52
MAOA P21397 3/20 0.48
MAPT P10636 5/20 0.47
ALOX15 P16050 4/20 0.47
TDP1 Q9NUW8 4/20 0.47
RECQL P46063 4/20 0.47
LMNA P02545 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
CA2 P00918 3/20 0.47
KDM4E B2RXH2 3/20 0.47
EGFR P00533 2/20 0.47
FYN P06241 2/20 0.47
CYP3A4 P08684 2/20 0.47
MMP9 P14780 2/20 0.47
APEX1 P27695 2/20 0.47
BLM P54132 2/20 0.47
POLB P06746 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29469517 0.92 MAOA (0.52) ALDH1A1HPGDHSD17B10BCL2L1MAOA
SCHEMBL29455667 0.92 MAOA (0.52) ALDH1A1HPGDHSD17B10BCL2L1MAOA
SCHEMBL31534010 0.90 MAOA (0.50) ALDH1A1HPGDHSD17B10BCL2L1MAOA
SCHEMBL31623901 0.90 MAOA (0.50) ALDH1A1HPGDHSD17B10BCL2L1MAOA
SCHEMBL29837181 0.86 MAOA (0.56) ALDH1A1HPGDHSD17B10BCL2L1MAOA
SCHEMBL2729251 0.86 MAOA (0.56) ALDH1A1HPGDHSD17B10BCL2L1MAOA
SCHEMBL5596876 0.85 ALDH1A1 (0.44) ALDH1A1HPGDHSD17B10BCL2L1MAOA
SCHEMBL29623192 0.85 ALDH1A1 (0.67) ALDH1A1HPGDHSD17B10BCL2L1MAOA
SCHEMBL28574 0.85 ALDH1A1 (0.67) ALDH1A1HPGDHSD17B10BCL2L1MAOA
SCHEMBL30442890 0.85 ALDH1A1 (0.67) ALDH1A1HPGDHSD17B10BCL2L1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829854-B1 PROCESS FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2013-09-04 EP disclosed
US-7629485-B2 Process for producing aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-12-08 US disclosed
US-20080177099-A1 Process for Producing Aromatic Carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2008-07-24 US disclosed
EP-1829854-A1 PROCESS FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2007-09-05 EP disclosed
EP-1016648-B1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES ASAHI CHEMICAL IND (JP) 2003-05-14 EP disclosed
EP-0855384-B1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATE ASAHI CHEMICAL IND (JP) 2001-12-12 EP disclosed
US-6262210-B1 TRANSESTERIFYING DIALKYL CARBONATE, ALKYL ARYL CARBONATE OR MIXTURE WITH AROMATIC MONOHYDROXY COMPOUND IN PRESENCE OF METAL CONTAINING CATALYST TO OBTAIN HIGH BOILING POINT REACTION MIXTURE CONTAINING AROMATIC CARBONATE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-07-17 US disclosed
EP-1016648-A1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-07-05 EP disclosed
US-5872275-A Process for the producing of aromatic carbonate ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1999-02-16 US disclosed
EP-0855384-A1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATE Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1998-07-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080177099-A1 Process for Producing Aromatic Carbonate DCLK1, ALK, DCLK3 ALDH1A1 1791/4885HPGD 3545/4885HSD17B10 963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.