Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.40 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9277097 | 0.93 | — | — | |
| SCHEMBL31367869 | 0.82 | NAAA (0.41) | NAAACES2EPHX1CA1CA2 | |
| SCHEMBL31169661 | 0.82 | NAAA (0.41) | NAAACES2EPHX1CA1CA2 | |
| SCHEMBL14719802 | 0.81 | NAAA (0.46) | NAAACES2EPHX1CYP3A4TSHR | |
| SCHEMBL11001294 | 0.81 | TSHR (0.45) | CES2CA1CA2MEN1CYP3A4 | |
| SCHEMBL2005556 | 0.79 | SOAT1 (0.33) | MEN1CYP3A4KMT2ATSHR | |
| SCHEMBL10615595 | 0.79 | TSHR (0.50) | NAAACES2EPHX1MEN1MAPT | |
| SCHEMBL124892 | 0.79 | ALDH1A1 (0.50) | NAAACES2EPHX1CYP3A4TSHR | |
| SCHEMBL1526422 | 0.79 | NAAA (0.45) | NAAACES2EPHX1MEN1KMT2A | |
| SCHEMBL7297683 | 0.79 | NAAA (0.45) | NAAACES2EPHX1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461681-A | Iridium-catalyzed N-phenyl-7 azaindole derivative and preparation method thereof | 陕西科技大学 | 2021-10-01 | — | — | CN | claimed |
| CN-110283103-B | Method for synthesizing α amino acid ester/amide by base-catalyzed decarboxylation amination | 北京理工大学 | 2020-08-04 | — | — | CN | claimed |
| CN-110878034-A | Method for preparing amine compound by base-catalyzed decarboxylation amination | 北京理工大学 | 2020-03-13 | — | — | CN | claimed |
| CN-110283103-A | A kind of decarboxylation amination of base catalysis prepares amino-acid ester/amide method | 北京理工大学 | 2019-09-27 | — | — | CN | claimed |
| CN-102216257-A | GABA conjugates and methods of use thereof | KYPHIA PHARMACEUTICALS INC | 2011-10-12 | — | — | CN | claimed |
| CN-101898977-A | GABA (Gamma-Aminobutyric Acid) conjugates and using method thereof | FENG XU | 2010-12-01 | — | — | CN | claimed |
| CN-101291916-A | 9-aminocarbonyl substituted derivatives of glycylcyclines | WYETH CORP (US) | 2008-10-22 | — | — | CN | claimed |
| CN-113461681-B | Iridium-catalyzed N-phenyl-7 azaindole derivative and preparation method thereof | 陕西科技大学 | 2024-03-15 | — | — | CN | disclosed |
| CN-113461681-A | Iridium-catalyzed N-phenyl-7 azaindole derivative and preparation method thereof | 陕西科技大学 | 2021-10-01 | — | — | CN | disclosed |
| CN-110283103-B | Method for synthesizing α amino acid ester/amide by base-catalyzed decarboxylation amination | 北京理工大学 | 2020-08-04 | — | — | CN | disclosed |
| CN-110283103-B | Method for synthesizing α amino acid ester/amide by base-catalyzed decarboxylation amination | 北京理工大学 | 2020-08-04 | — | — | CN | disclosed |
| CN-110878034-A | Method for preparing amine compound by base-catalyzed decarboxylation amination | 北京理工大学 | 2020-03-13 | — | — | CN | disclosed |
| CN-110283103-A | A kind of decarboxylation amination of base catalysis prepares amino-acid ester/amide method | 北京理工大学 | 2019-09-27 | — | — | CN | disclosed |
| CN-1220760-C | Bleaching composition | PROCTER & GAMBLE (US) | 2005-09-28 | — | — | CN | disclosed |
| CN-1260830-A | Bleach compositions | PROCTER & GAMBLE (US) | 2000-07-19 | — | — | CN | disclosed |
| EP-0269853-B1 | EPOXIDIZED ISOCYANATES AND PROCESS FOR THEIR PREPARATION | AMERICAN CYANAMID COMPANY (US) | 1990-05-09 | — | — | EP | disclosed |
| US-4788303-A | Epoxidized isocyanates and process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0269853-A1 | Epoxidized isocyanates and process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1988-06-08 | — | — | EP | disclosed |
| US-4731428-A | Epoxidized isocyanates and process for their preparation | AMERICAN CYANAMID CO. (US) | 1988-03-15 | — | — | US | disclosed |
| US-4160077-A | Process of crosslinking unsaturated hydrocarbon polymers employing novel carbamates | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-07-03 | — | — | US | disclosed |