Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127720 | 0.86 | CA1 (0.52) | CA1CA2CA12CA7CA9 | |
| SCHEMBL6784218 | 0.80 | CA12 (0.49) | CA1CA2CA12CA7CA9 | |
| SCHEMBL8026225 | 0.78 | CA1 (0.45) | CA1CA2CA12CA7CA9 | |
| SCHEMBL9195826 | 0.78 | CA1 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL21179316 | 0.78 | THRB (0.37) | KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL3891739 | 0.77 | CA12 (0.44) | CA1CA2CA12CA7CA9 | |
| SCHEMBL27847162 | 0.77 | CA1 (0.44) | CA1CA2CA12CA7CA9 | |
| SCHEMBL27556890 | 0.77 | CA1 (0.44) | CA1CA2CA12CA7CA9 | |
| SCHEMBL148613 | 0.75 | ALB (0.42) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7260462 | 0.74 | L3MBTL1 (0.42) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1493744-B1 | Tropane analogs and methods for inhibition of monoamine transport | ORGANIX INC (US) | 2009-11-25 | — | — | EP | claimed |
| US-4889553-A | Herbicides | SCHERING AGROCHEMICALS (GB) | 1989-12-26 | — | — | US | claimed |
| EP-0246749-A2 | Triazole herbicides | AgrEvo UK Limited (GB) | 1987-11-25 | — | — | EP | claimed |
| CN-101720437-A | methods, compositions and uses thereof | RENASCI DEVELOPMENTS LTD | 2010-06-02 | — | — | CN | disclosed |
| CN-1091100-C | N-arylsulfilimine compounds and their use as catalysts for the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 2002-09-18 | — | — | CN | disclosed |
| US-6114580-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0888297-B1 | N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-08-30 | — | — | EP | disclosed |
| US-5973148-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 1999-10-26 | — | — | US | disclosed |
| CN-1216040-A | N-arylsulfilimine compounds and their use as catalysts in preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 1999-05-05 | — | — | CN | disclosed |
| EP-0888297-A1 | N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | Dow AgroSciences LLC (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1998021178-A1 | N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 1998-05-22 | — | — | WO | disclosed |
| US-5389642-A | Exhibit antagonistic properties toward angiotensin(II); useful for treatment of hypertensioni, aldosteronism, cardiac insufficiency, increased intraocular pressure and disorders of the central nervous system | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |
| CN-1094044-A | Imidazopyridine | MERCK PATENT GMBH (DE) | 1994-10-26 | — | — | CN | disclosed |
| EP-0602521-A1 | Imidazopyridines | MERCK PATENT GmbH (DE) | 1994-06-22 | — | — | EP | disclosed |
| US-4889553-A | Herbicides | SCHERING AGROCHEMICALS (GB) | 1989-12-26 | — | — | US | disclosed |
| EP-0246749-A2 | Triazole herbicides | AgrEvo UK Limited (GB) | 1987-11-25 | — | — | EP | disclosed |