Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 5/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4390477 | 0.90 | F10 (0.38) | F10IDO1HRH4IDH1ALDH1A1 | |
| SCHEMBL4392578 | 0.89 | KCNH2 (0.35) | F10KCNH2 | |
| SCHEMBL4386121 | 0.89 | KCNH2 (0.40) | F10KCNH2 | |
| SCHEMBL1385204 | 0.85 | F10 (0.39) | F10 | |
| SCHEMBL1387128 | 0.84 | F10 (0.43) | F10IDO1HRH4IDH1ALDH1A1 | |
| SCHEMBL4396056 | 0.78 | F10 (0.36) | F10KCNH2 | |
| SCHEMBL1385505 | 0.78 | F10 (0.39) | F10IDH1ALDH1A1LMNAMAPT | |
| SCHEMBL4390831 | 0.78 | F10 (0.41) | F10IDH1KCNH2 | |
| SCHEMBL1385998 | 0.74 | F10 (0.40) | F10 | |
| SCHEMBL1386665 | 0.73 | F10 (0.42) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |