Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162314 | 0.79 | TSHR (0.37) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL4989700 | 0.76 | TDP1 (0.35) | TSHRTDP1HSD17B10 | |
| SCHEMBL797852 | 0.71 | — | — | |
| SCHEMBL9482612 | 0.70 | CYP3A4 (0.39) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL10690119 | 0.70 | — | — | |
| SCHEMBL9547338 | 0.70 | — | — | |
| SCHEMBL4992998 | 0.69 | HDAC6 (0.35) | TDP1 | |
| Hydrochloric Acid SCHEMBL11684897 | 0.69 | TSHR (0.38) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL16264823 | 0.69 | TSHR (0.42) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL6549396 | 0.69 | TSHR (0.42) | TSHRCYP3A4TDP1MAPTCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473671-B2 | Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2009-01-06 | — | — | US | disclosed |
| US-7331920-B2 | Glycopeptide antibiotics, combinational libraries of glycopeptide antibiotics and methods of producing same | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2008-02-19 | — | — | US | disclosed |
| US-20050075483-A1 | Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same | TRUSTEES OF PRINCETON UNIVERSITY | 2005-04-07 | — | — | US | disclosed |
| US-20040106772-A1 | Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same | TRUSTEES OF PRINCETON UNIVERSITY, THE | 2004-06-03 | — | — | US | disclosed |
| US-6710168-B1 | VANCOMYCIN DERIVATIVES | THE TRUSTEES OF THE UNIVERSITY OF PRINCETON | 2004-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106772-A1 | Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same | NPR1, NPR3, OSTC | TSHR 463/4885CYP3A4 3890/4885TDP1 3513/4885 |
| US-20050075483-A1 | Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same | ARSA, STS, GARS1 | TSHR 232/4885CYP3A4 1108/4885TDP1 4822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.