Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 5/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3587268 | 0.86 | AR (0.41) | ALDH1A1HPGDXDHAR | |
| SCHEMBL3585536 | 0.84 | ALDH1A1 (0.41) | ALDH1A1HPGDXDHAR | |
| SCHEMBL3588914 | 0.84 | AR (0.41) | XDHSLC22A12AR | |
| SCHEMBL3585538 | 0.80 | KDM4E (0.39) | ALDH1A1AR | |
| SCHEMBL3580264 | 0.77 | KDM4E (0.40) | ALDH1A1HPGDAR | |
| SCHEMBL3583722 | 0.75 | XDH (0.41) | ALDH1A1HPGDXDH | |
| SCHEMBL3589302 | 0.74 | XDH (0.41) | XDHSLC22A12AR | |
| SCHEMBL3593046 | 0.72 | XDH (0.42) | XDHSLC22A12 | |
| SCHEMBL3583718 | 0.72 | XDH (0.42) | ALDH1A1HPGDXDH | |
| SCHEMBL3583163 | 0.72 | XDH (0.45) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2128136-A1 | 2-PHENYLNICOTINIC ACID DERIVATIVE | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2009-12-02 | — | — | EP | disclosed |