Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | RBBP9 | O75884 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 3/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5609781 | 0.80 | ALDH1A1 (0.57) | ALDH1A1RBBP9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5609136 | 0.80 | ALDH1A1 (0.69) | ALDH1A1RBBP9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28027939 | 0.80 | ALDH1A1 (0.67) | ALDH1A1RBBP9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL12801063 | 0.77 | ALDH1A1 (0.64) | ALDH1A1RBBP9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL14152809 | 0.77 | ALDH1A1 (0.64) | ALDH1A1RBBP9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL158422 | 0.76 | — | — | |
| SCHEMBL247631 | 0.76 | — | — | |
| SCHEMBL28219561 | 0.76 | ALDH1A1 (0.68) | ALDH1A1RBBP9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10831806 | 0.76 | ALDH1A1 (0.52) | ALDH1A1RBBP9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL17844700 | 0.74 | ALDH1A1 (0.55) | ALDH1A1RBBP9CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751146-B1 | PYRIDINYL- OR PYRIMIDINYL THIAZOLES WITH PROTEIN KINASE INHIBITING ACTIVITY | CYCLACEL LTD (GB) | 2009-12-02 | — | — | EP | disclosed |
| US-20080318954-A1 | Compounds | CYCLACEL LIMITED (GB) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318954-A1 | Compounds | CBR3, NR3C2, NR5A1 | ALDH1A1 1920/4885RBBP9 1727/4885CYP1A2 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.