Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 3/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4390222 | 0.88 | HCAR2 (0.34) | — | |
| SCHEMBL13591000 | 0.81 | NPSR1 (0.36) | — | |
| SCHEMBL13591036 | 0.79 | CYP1A2 (0.31) | — | |
| SCHEMBL4389249 | 0.78 | ADAM17 (0.32) | ADAM17MMP13MMP9 | |
| SCHEMBL4388128 | 0.76 | ADAM17 (0.32) | ADAM17 | |
| SCHEMBL5634457 | 0.71 | ADAM17 (0.32) | ADAM17 | |
| SCHEMBL6364194 | 0.70 | — | — | |
| SCHEMBL14368391 | 0.70 | NPY5R (0.36) | — | |
| SCHEMBL4857695 | 0.69 | MEN1 (0.39) | — | |
| SCHEMBL4858905 | 0.69 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569922-B1 | 1,2,4-THIADIAZOLE COMPOUNDS AND ARTHROPOD CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2009-12-02 | — | — | EP | disclosed |
| US-7301032-B2 | 1,2,4-thiadiazole compounds and arthropod controlling composition containing the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2007-11-27 | — | — | US | disclosed |
| US-7301032-B2 | 1,2,4-thiadiazole compounds and arthropod controlling composition containing the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2007-11-27 | — | — | US | disclosed |
| US-20060052422-A1 | 1,2,4-Thiadiazole compounds and arthropod controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-03-09 | — | — | US | disclosed |
| EP-1569922-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND ARTHROPOD CONTROLLING COMPOSITION CONTAINING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004046125-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND ARTHROPOD CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052422-A1 | 1,2,4-Thiadiazole compounds and arthropod controlling composition containing the same | NAT1, C1S, C1R | ADAM17 1573/4885MMP13 3889/4885MMP9 4009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.