Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4392230 | 0.85 | TAAR1 (0.57) | TAAR1SLC6A2ESR1ESR2SLC7A5 | |
| SCHEMBL16389855 | 0.84 | MAOA (0.39) | ALDH1A1TSHRTDP1 | |
| SCHEMBL8897405 | 0.81 | EPHX1 (0.54) | TAAR1SLC6A2SLC7A5 | |
| SCHEMBL1839615 | 0.80 | SLC6A2 (0.50) | TAAR1SLC6A2ESR1ESR2SLC7A5 | |
| SCHEMBL4394050 | 0.77 | TAAR1 (0.61) | TAAR1SLC6A2ESR1ESR2SLC7A5 | |
| SCHEMBL11513417 | 0.76 | TAAR1 (0.43) | TAAR1SLC6A2SLC7A5 | |
| SCHEMBL8148589 | 0.76 | TAAR1 (0.46) | TAAR1SLC6A2ESR1ESR2SLC7A5 | |
| SCHEMBL972278 | 0.75 | SLC7A5 (0.57) | TAAR1SLC6A2ESR1ESR2SLC7A5 | |
| SCHEMBL972279 | 0.75 | SLC7A5 (0.57) | TAAR1SLC6A2ESR1ESR2SLC7A5 | |
| SCHEMBL7630188 | 0.75 | PPARA (0.56) | SLC6A2ESR1SLC7A5ALDH1A1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227390-B2 | Binder resin for friction material, binder resin composition for friction material, composite material for friction material containing the same, friction material and production method thereof | AKEBONO BRAKE INDUSTRY CO., LTD. (JP) | 2012-07-24 | — | — | US | disclosed |
| US-20090137434-A1 | BINDER RESIN FOR FRICTION MATERIAL, BINDER RESIN COMPOSITION FOR FRICTION MATERIAL, COMPOSITE MATERIAL FOR FRICTION MATERIAL CONTAINING THE SAME, FRICTION MATERIAL AND PRODUCTION METHOD THEREOF | AKEBONO BRAKE INDUSTRY CO., LTD (JP) | 2009-05-28 | — | — | US | disclosed |