Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 6/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4394050 | 0.80 | TAAR1 (0.61) | TAAR1SLC6A2ESR1ESR2SLC7A5 | |
| Hydroxyamphetamine SCHEMBL125440 | 0.77 | TAAR1 (1.00) | TAAR1SLC6A2ESR1ESR2SLC6A4 | |
| Hydroxyamphetamine SCHEMBL125442 | 0.77 | TAAR1 (1.00) | TAAR1SLC6A2ESR1ESR2SLC6A4 | |
| (S)-P-Hydroxyamphetamine SCHEMBL256809 | 0.77 | TAAR1 (1.00) | TAAR1SLC6A2ESR1ESR2SLC6A4 | |
| SCHEMBL4392230 | 0.77 | TAAR1 (0.57) | TAAR1SLC6A2ESR1ESR2SLC7A5 | |
| Hydroxyamphetamine SCHEMBL221291 | 0.75 | TAAR1 (0.95) | TAAR1SLC6A2ESR1ESR2SLC6A4 | |
| Hydroxyamphetamine SCHEMBL219710 | 0.75 | TAAR1 (0.95) | TAAR1SLC6A2ESR1ESR2SLC6A4 | |
| Hydroxyamphetamine SCHEMBL221649 | 0.75 | TAAR1 (1.00) | TAAR1SLC6A2ESR1ESR2SLC6A4 | |
| (S)-P-Hydroxyamphetamine SCHEMBL9707065 | 0.75 | TAAR1 (1.00) | TAAR1SLC6A2ESR1ESR2SLC6A4 | |
| Hydroxyamphetamine SCHEMBL11539011 | 0.75 | TAAR1 (0.95) | TAAR1SLC6A2ESR1ESR2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227390-B2 | Binder resin for friction material, binder resin composition for friction material, composite material for friction material containing the same, friction material and production method thereof | AKEBONO BRAKE INDUSTRY CO., LTD. (JP) | 2012-07-24 | — | — | US | disclosed |
| US-20090137434-A1 | BINDER RESIN FOR FRICTION MATERIAL, BINDER RESIN COMPOSITION FOR FRICTION MATERIAL, COMPOSITE MATERIAL FOR FRICTION MATERIAL CONTAINING THE SAME, FRICTION MATERIAL AND PRODUCTION METHOD THEREOF | AKEBONO BRAKE INDUSTRY CO., LTD (JP) | 2009-05-28 | — | — | US | disclosed |