SCHEMBL4392276

SCHEMBL4392276

Cc1ccc(S(=O)(=O)N2CCC(N3C(=O)OCc4ccccc43)CC2)cc1O

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 9/20 0.59
OXTR P30559 10/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3152698 0.91 HTR6 (0.62) HTR6OXTR
SCHEMBL4399484 0.89 HTR6 (0.46) HTR6
SCHEMBL4393649 0.87 HTR6 (0.65) HTR6
SCHEMBL3140363 0.86 HTR6 (0.59) HTR6OXTR
SCHEMBL3152839 0.86 HTR6 (0.59) HTR6OXTR
SCHEMBL3156992 0.86 HTR6 (0.66) HTR6OXTR
SCHEMBL3152760 0.85 HTR6 (0.65) HTR6OXTR
SCHEMBL3148520 0.84 HTR6 (0.69) HTR6OXTR
SCHEMBL3143802 0.84 HTR6 (0.63) HTR6OXTR
SCHEMBL3148904 0.83 HTR6 (0.66) HTR6OXTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1648886-B1 BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS ESTEVE LABOR DR (ES) 2009-12-09 EP claimed