Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3153162 | 0.91 | HTR6 (0.48) | HTR6MAPTKMT2AALDH1A1USP2 | |
| SCHEMBL4392276 | 0.89 | HTR6 (0.59) | HTR6 | |
| SCHEMBL3142474 | 0.89 | HTR6 (0.52) | HTR6KMT2AALDH1A1 | |
| SCHEMBL3155997 | 0.86 | HTR6 (0.46) | HTR6MAPTALDH1A1HTT | |
| SCHEMBL3152980 | 0.86 | HTR6 (0.50) | HTR6ALDH1A1 | |
| SCHEMBL3156877 | 0.86 | HTR6 (0.54) | HTR6KMT2AALDH1A1USP2LMNA | |
| SCHEMBL3152816 | 0.86 | HTR6 (0.49) | HTR6ALDH1A1 | |
| SCHEMBL3156964 | 0.85 | HTR6 (0.49) | HTR6 | |
| SCHEMBL3138639 | 0.85 | HTR6 (0.47) | HTR6MAPTALDH1A1TSHRHTT | |
| SCHEMBL3153657 | 0.85 | HTR6 (0.55) | HTR6ALDH1A1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-B1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2009-12-09 | — | — | EP | claimed |