Dexfosfoserine

Dexfosfoserine

SCHEMBL439230

N[C@@H](COP(=O)(O)O)C(=O)O.O=C(O)CCC(=O)C(=O)O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.45
SLC13A3 Q8WWT9 1/20 0.45
EGLN1 Q9GZT9 1/20 0.45
OR51E2 Q9H255 1/20 0.45
PGK1 P00558 1/20 0.44
PGK2 P07205 1/20 0.44
GRM8 O00222 2/20 0.42
GRM6 O15303 2/20 0.42
GRM7 Q14831 2/20 0.42
GRM4 Q14833 2/20 0.42
PGD P52209 1/20 0.42
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GSR P00390 1/20 0.40
CYP1A2 P05177 1/20 0.40
GRIK1 P39086 1/20 0.40
GRM5 P41594 1/20 0.40
GRIA1 P42261 1/20 0.40
GRIA2 P42262 1/20 0.40
GRIA3 P42263 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dexfosfoserine SCHEMBL6846 0.84 PGK1 (0.59) PGK1PGK2PGDP2RY10GPR34
Dexfosfoserine SCHEMBL29427835 0.84 PGK1 (0.59) PGK1PGK2PGDP2RY10GPR34
Dexfosfoserine SCHEMBL6847 0.84 PGK1 (0.59) PGK1PGK2PGDP2RY10GPR34
Dexfosfoserine SCHEMBL20798048 0.84 PGK1 (0.59) PGK1PGK2PGDP2RY10GPR34
Dexfosfoserine SCHEMBL18301530 0.83 GRM8 (0.62) PGK1PGK2GRM8GRM6GRM7
Dexfosfoserine SCHEMBL4285878 0.82 PGK1 (0.57) PGK1PGK2PGDP2RY10GPR34
Dexfosfoserine SCHEMBL4285884 0.82 PGK1 (0.57) PGK1PGK2PGDP2RY10GPR34
Dexfosfoserine SCHEMBL5654871 0.82 PGK1 (0.57) PGK1PGK2PGDP2RY10GPR34
Dexfosfoserine SCHEMBL10496255 0.82 PGK1 (0.57) PGK1PGK2PGDP2RY10GPR34
Dexfosfoserine SCHEMBL27915644 0.82 PGK1 (0.57) PGK1PGK2PGDP2RY10GPR34

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230383318-A1 METHODS AND SYSTEMS FOR CHEMOAUTOTROPHIC PRODUCTION OF ORGANIC COMPOUNDS GINKGO BIOWORKS, INC. (US) 2023-11-30 US disclosed
US-11697829-B2 Chemoautotrophic cells comprising an engineered carbon fixation pathway GINKGO BIOWORKS, INC. (US) 2023-07-11 US disclosed
US-20230107986-A1 METHODS AND SYSTEMS FOR METHYLOTROPHIC PRODUCTION OF ORGANIC COMPOUNDS GINKGO BIOWORKS, INC. (US) 2023-04-06 US disclosed
US-20210010037-A1 METHODS AND SYSTEMS FOR CHEMOAUTOTROPHIC PRODUCTION OF ORGANIC COMPOUNDS GINKGO BIOWORKS, INC. (US) 2021-01-14 US disclosed
US-10801045-B2 Methods for making chemoautotrophic cells by engineering an energy conversion pathway and a carbon fixation pathway GINKGO BIOWORKS, INC. (US) 2020-10-13 US disclosed
US-20180223317-A1 METHODS AND SYSTEMS FOR CHEMOAUTOTROPHIC PRODUCTION OF ORGANIC COMPOUNDS GINKGO BIOWORKS, INC. 2018-08-09 US disclosed
US-20180216120-A1 METHODS AND SYSTEMS FOR METHYLOTROPHIC PRODUCTION OF ORGANIC COMPOUNDS GINKGO BIOWORKS, INC. 2018-08-02 US disclosed
US-9902980-B2 Methods and systems for chemoautotrophic production of organic compounds GINKGO BIOWORKS, INC. (US) 2018-02-27 US disclosed
US-20150315599-A1 Methods and Systems for Methylotrophic Production of Organic Compounds GINKGO BIOWORKS, INC. 2015-11-05 US disclosed
US-20150037853-A1 Methods and Systems for Chemoautotrophic Production of Organic Compounds GINKGO BIOWORKS, INC. 2015-02-05 US disclosed
US-8349587-B2 Methods and systems for chemoautotrophic production of organic compounds GINKGO BIOWORKS, INC. (US) 2013-01-08 US disclosed
US-20120064622-A1 Methods and Systems for Chemoautotrophic Production of Organic Compounds GINKGO BIOWORKS (US) 2012-03-15 US disclosed