Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 6/20 | 0.40 |
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1396396 | 0.82 | CA12 (0.41) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL3287158 | 0.82 | CA12 (0.41) | CA12CA1CA9 | |
| SCHEMBL7706827 | 0.80 | CA1 (0.50) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL5292779 | 0.78 | ACHE (0.45) | CA12CA1CA9CA2 | |
| SCHEMBL6810932 | 0.76 | HAO1 (0.38) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL3182564 | 0.75 | CA12 (0.46) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL8055180 | 0.75 | ACHE (0.50) | CA12CA1CA9GRM5CA2 | |
| SCHEMBL30940206 | 0.75 | CA12 (0.43) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL4004898 | 0.74 | CYP3A4 (0.47) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL2329760 | 0.74 | ACHE (0.50) | CA12CA1CA9PREPHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112274-B1 | CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ P (US) | 2009-12-09 | — | — | EP | disclosed |
| EP-0254051-B1 | Chemiluminescent 1,2-dioxetane compounds | UNIV WAYNE STATE (US) | 1994-08-31 | — | — | EP | disclosed |