Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 2/20 | 0.35 |
| ▸ | FABP7 | O15540 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3287158 | 0.83 | CA12 (0.41) | CA12CA1CA9 | |
| SCHEMBL4392522 | 0.82 | CA12 (0.40) | CA12CA1CA9HSP90AA1HSP90AB1 | |
| SCHEMBL7706827 | 0.82 | CA1 (0.50) | CA12CA1CA9HSP90AA1HSP90AB1 | |
| SCHEMBL6810932 | 0.80 | HAO1 (0.38) | CA12CA1CA9HAO1HSP90AA1 | |
| SCHEMBL9051730 | 0.79 | PREP (0.43) | CA12CA1CA9HAO1PREP | |
| SCHEMBL28574194 | 0.78 | FABP7 (0.40) | CA12CA1CA9HAO1FABP7 | |
| SCHEMBL3182564 | 0.77 | CA12 (0.46) | CA12CA1CA9HSP90AA1HSP90AB1 | |
| SCHEMBL24724730 | 0.76 | KDM4E (0.39) | EGFR | |
| SCHEMBL30940206 | 0.76 | CA12 (0.43) | CA12CA1CA9HSP90AA1HSP90AB1 | |
| SCHEMBL2329760 | 0.75 | ACHE (0.50) | CA12CA1CA9HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240190823-A1 | NRF2 INHIBITORS AND USES THEREOF | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2024-06-13 | — | — | US | disclosed |
| EP-2288612-B1 | GABAA RECEPTOR MODULATORS | GABATHER AB (SE) | 2015-07-29 | — | — | EP | disclosed |
| US-8809355-B2 | GABAA receptor modulators | INNOVATIONSPATENT SVERIGE AB (SE) | 2014-08-19 | — | — | US | disclosed |
| US-20110092525-A1 | GABAA RECEPTOR MODULATORS | GABATHER AB (SE) | 2011-04-21 | — | — | US | disclosed |
| EP-2288612-A1 | GABAA RECEPTOR MODULATORS | Forskarpatent i Syd AB (SE) | 2011-03-02 | — | — | EP | disclosed |
| WO-2009123537-A1 | GABAa RECEPTOR MODULATORS | FORSKARPATENT I SYD AB (SE) | 2009-10-08 | — | — | WO | disclosed |
| WO-2009026345-A1 | THIAZOLIDINONE COMPOUNDS, AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092525-A1 | GABAA RECEPTOR MODULATORS | GABRA5, GABRA1, GABRA2 | CA12 3840/4885CA1 1506/4885CA9 2046/4885 |
| US-20240190823-A1 | NRF2 INHIBITORS AND USES THEREOF | KEAP1, NFE2L2, NQO1 | CA12 3731/4885CA1 3513/4885CA9 800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.