Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18394315 | 0.81 | NOTUM (1.00) | NOTUM | |
| SCHEMBL31141617 | 0.78 | VNN1 (0.55) | NOTUM | |
| SCHEMBL3610229 | 0.77 | NOTUM (0.67) | NOTUM | |
| SCHEMBL2291570 | 0.76 | NOTUM (0.67) | NOTUM | |
| SCHEMBL8270247 | 0.76 | NOTUM (1.00) | NOTUM | |
| SCHEMBL13050395 | 0.76 | NOTUM (0.67) | NOTUM | |
| SCHEMBL18395243 | 0.76 | NOTUM (1.00) | NOTUM | |
| SCHEMBL5542637 | 0.75 | NOTUM (1.00) | NOTUM | |
| SCHEMBL3270146 | 0.74 | NOTUM (0.74) | NOTUM | |
| SCHEMBL13050396 | 0.74 | NOTUM (0.63) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1959951-B1 | HETEROARYL SUBSTITUTED PIPERIDINE DERIVATIVES AS L-CPT1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-12-23 | — | — | EP | disclosed |