Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18394315 | 0.85 | NOTUM (1.00) | NOTUM | |
| SCHEMBL4392841 | 0.74 | NOTUM (0.68) | NOTUM | |
| SCHEMBL31141681 | 0.69 | NOTUM (0.63) | NOTUM | |
| SCHEMBL1500607 | 0.69 | NOTUM (0.64) | NOTUM | |
| SCHEMBL1500521 | 0.68 | NOTUM (0.67) | NOTUM | |
| SCHEMBL5542943 | 0.68 | NOTUM (0.92) | NOTUM | |
| SCHEMBL31141703 | 0.66 | NOTUM (0.57) | NOTUM | |
| SCHEMBL2186256 | 0.66 | MMP3 (0.47) | — | |
| SCHEMBL5541925 | 0.65 | NOTUM (1.00) | NOTUM | |
| SCHEMBL2184380 | 0.65 | KIF11 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030722-A1 | GLUCAGON RECEPTOR ANTAGONIST COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK SHARP & DOHME CORP. (US) | 2010-03-18 | — | — | WO | disclosed |