Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ZDHHC7 | Q9NXF8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442233 | 1.00 | ACE2 (0.46) | ACE2LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL23761385 | 0.93 | ACE2 (0.37) | ACE2EPHX1TSHRCA1 | |
| SCHEMBL442805 | 0.86 | HRH4 (0.37) | EPHX1TSHR | |
| SCHEMBL443152 | 0.85 | ACE2 (0.49) | ACE2ZDHHC20ZDHHC2EPHX1FAAH | |
| SCHEMBL440464 | 0.85 | ACE2 (0.49) | ACE2ZDHHC20ZDHHC2EPHX1FAAH | |
| SCHEMBL440561 | 0.85 | LMNA (0.42) | LCKPPARDZDHHC20ZDHHC2EPHX1 | |
| SCHEMBL443990 | 0.85 | LMNA (0.42) | LCKPPARDZDHHC20ZDHHC2EPHX1 | |
| SCHEMBL6117766 | 0.85 | LMNA (0.42) | LCKPPARDZDHHC20ZDHHC2EPHX1 | |
| SCHEMBL442618 | 0.85 | LMNA (0.42) | LCKPPARDZDHHC20ZDHHC2EPHX1 | |
| SCHEMBL440272 | 0.83 | LMNA (0.41) | LCKPPARDZDHHC20ZDHHC2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835368-B2 | Compounds and a method of lubricating an internal combustion engine | THE LUBRIZOL CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120065110-A1 | Compounds and a Method of Lubricating an Internal Combustion Engine | THE LUBRIZOL CORPORATION (US) | 2012-03-15 | — | — | US | disclosed |