Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL443990 | 0.98 | LMNA (0.42) | LMNAZDHHC20ZDHHC2LCKPPARD | |
| SCHEMBL442618 | 0.98 | LMNA (0.42) | LMNAZDHHC20ZDHHC2LCKPPARD | |
| SCHEMBL6117766 | 0.98 | LMNA (0.42) | LMNAZDHHC20ZDHHC2LCKPPARD | |
| SCHEMBL440561 | 0.98 | LMNA (0.42) | LMNAZDHHC20ZDHHC2LCKPPARD | |
| SCHEMBL442232 | 0.93 | LMNA (0.37) | LMNAZDHHC20ZDHHC2LCKPPARD | |
| SCHEMBL3466992 | 0.90 | ZDHHC20 (0.51) | LMNAZDHHC20ZDHHC2LCKPPARD | |
| SCHEMBL225597 | 0.88 | TSHR (0.50) | LMNACA2TSHRHTTPOLB | |
| SCHEMBL442233 | 0.83 | ACE2 (0.46) | ZDHHC20ZDHHC2LCKPPARDTSHR | |
| SCHEMBL439287 | 0.83 | ACE2 (0.46) | ZDHHC20ZDHHC2LCKPPARDTSHR | |
| SCHEMBL444035 | 0.81 | GNAI3 (0.47) | ZDHHC20ZDHHC2CA2DPP7EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835368-B2 | Compounds and a method of lubricating an internal combustion engine | THE LUBRIZOL CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120065110-A1 | Compounds and a Method of Lubricating an Internal Combustion Engine | THE LUBRIZOL CORPORATION (US) | 2012-03-15 | — | — | US | disclosed |