Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 7/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SCN4A | P35499 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2709313 | 0.79 | DPP4 (0.53) | PREPTGM2DPP4HSD17B10ALDH1A1 | |
| SCHEMBL2709311 | 0.79 | DPP4 (0.53) | PREPTGM2DPP4HSD17B10ALDH1A1 | |
| SCHEMBL4392886 | 0.79 | CYP3A4 (0.41) | PREPTGM2DPP4POLBCYP3A4 | |
| SCHEMBL2709456 | 0.78 | DPP4 (0.55) | PREPDPP4ALDH1A1L3MBTL1 | |
| SCHEMBL2708987 | 0.77 | DPP4 (0.42) | PREPDPP4CYP3A4 | |
| SCHEMBL2709078 | 0.77 | DPP4 (0.59) | PREPDPP4ALDH1A1L3MBTL1 | |
| SCHEMBL2710791 | 0.76 | GPR119 (0.44) | PREPDPP4ALDH1A1L3MBTL1 | |
| SCHEMBL2711952 | 0.76 | DPP4 (0.57) | PREPDPP4ALDH1A1L3MBTL1 | |
| SCHEMBL2708829 | 0.75 | DPP4 (0.41) | PREPTGM2DPP4HSD17B10 | |
| SCHEMBL2708280 | 0.75 | DPP4 (0.58) | PREPDPP4ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1950199-B1 | Proline derivatives and use thereof as drugs | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-12-02 | — | — | EP | disclosed |