Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 6/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.68 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.68 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.68 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.68 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.68 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.68 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.68 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.68 |
| ▸ | NPY1R | P25929 | 1/20 | 0.64 |
| ▸ | BCHE | P06276 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | ACACB | O00763 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | PARG | Q86W56 | 1/20 | 0.58 |
| ▸ | GBA1 | P04062 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4393007 | 1.00 | NPY5R (0.70) | NPY5RHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4551118 | 0.91 | ACACB (0.64) | NPY5RHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13768018 | 0.86 | NPY5R (0.73) | NPY5RHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23052424 | 0.86 | NPY5R (0.69) | NPY5RHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7023898 | 0.85 | HDAC3 (0.77) | NPY5RHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL932265 | 0.84 | NPY5R (0.66) | NPY5RHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13797011 | 0.84 | NPY5R (0.66) | NPY5RHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8208140 | 0.83 | HDAC3 (0.78) | NPY5RHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4007519 | 0.83 | HDAC3 (0.71) | NPY5RHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6584417 | 0.83 | HDAC3 (0.78) | NPY5RHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ACACA, ACACB, ACAT1 | NPY5R 890/4885HDAC3 190/4885HDAC4 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.