Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.47 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 4/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25217416 | 0.87 | NAMPT (0.47) | NAMPTPIK3CAPIK3CGLMNAF10 | |
| SCHEMBL12256553 | 0.83 | MAPK1 (0.45) | NAMPT | |
| SCHEMBL12992190 | 0.81 | TSHR (0.46) | NAMPTMTNR1AMTNR1BSMN1; SMN2ALDH1A1 | |
| SCHEMBL3390804 | 0.79 | MCL1 (0.45) | NAMPTPIK3CAPIK3CGALDH1A1POLB | |
| SCHEMBL21139472 | 0.79 | NAMPT (0.55) | NAMPTSMN1; SMN2LMNAMAPTPOLB | |
| SCHEMBL12329647 | 0.78 | NAMPT (0.42) | NAMPTPIK3CAPIK3CGLMNAPOLB | |
| SCHEMBL18381246 | 0.78 | SMN1; SMN2 (0.46) | NAMPTSMN1; SMN2LMNAPTGS1F10 | |
| SCHEMBL31369919 | 0.78 | NAMPT (0.41) | NAMPTPIK3CAPIK3CGLMNAPTGS1 | |
| SCHEMBL16812917 | 0.77 | MEN1 (0.40) | NAMPTKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL18381439 | 0.76 | NAMPT (0.41) | NAMPTKDM4EPIK3CAPIK3CGSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |