Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31369367 | 0.84 | AGTR1 (0.38) | SLC40A1CHRM5CHRM4CHRM1CYP2C9 | |
| SCHEMBL1768417 | 0.82 | CYP11B1 (0.41) | CHRM5CYP11B1CYP11B2TBXAS1CHRM4 | |
| SCHEMBL25217416 | 0.81 | NAMPT (0.47) | NAMPTSLC40A1PIK3CAPIK3CGCHRM5 | |
| SCHEMBL18381246 | 0.79 | SMN1; SMN2 (0.46) | NAMPTTBXAS1LMNAPTGS1PTGS2 | |
| SCHEMBL25455194 | 0.78 | CHRM4 (0.37) | NAMPTCHRM5CHRM4CHRM1CYP2C9 | |
| SCHEMBL4393099 | 0.78 | QPCT (0.47) | NAMPTPIK3CAPIK3CGLMNAPTGS1 | |
| SCHEMBL18381439 | 0.76 | NAMPT (0.41) | NAMPTPIK3CAPIK3CGCYP11B1CYP11B2 | |
| SCHEMBL16310127 | 0.76 | NAMPT (0.38) | NAMPTCHRM5CHRM4CHRM1CYP2C9 | |
| SCHEMBL14415982 | 0.75 | CHRM5 (0.40) | NAMPTCHRM5CHRM4CHRM1CYP2C9 | |
| SCHEMBL9241438 | 0.75 | NAMPT (0.39) | NAMPTPIK3CAPIK3CGCHRM5CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | claimed |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | NAMPT 3710/4885SLC40A1 1589/4885PIK3CA 4621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.