Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.45 |
| ▸ | NAMPT | P43490 | 4/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12992190 | 0.80 | TSHR (0.46) | NAMPTALDH1A1 | |
| SCHEMBL25217416 | 0.79 | NAMPT (0.47) | NAMPTF10PIK3CAPIK3CGPRMT5 | |
| SCHEMBL18381246 | 0.77 | SMN1; SMN2 (0.46) | NAMPTF10 | |
| SCHEMBL5632632 | 0.76 | ACE2 (0.38) | MCL1 | |
| SCHEMBL4600447 | 0.76 | ACE2 (0.38) | MCL1 | |
| SCHEMBL14602509 | 0.76 | ACACB (0.43) | MCL1CYP11B1CYP11B2NTRK1 | |
| SCHEMBL12329647 | 0.74 | NAMPT (0.42) | NAMPTF10PIK3CAPIK3CGPRMT5 | |
| SCHEMBL21139472 | 0.72 | NAMPT (0.55) | NAMPTPRMT5WDR77POLBGAA | |
| SCHEMBL12299356 | 0.72 | NAMPT (0.39) | NAMPTF10PIK3CAPIK3CGPRMT5 | |
| SCHEMBL31369919 | 0.71 | NAMPT (0.41) | NAMPTPIK3CAPIK3CGCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430018-B1 | METHOD FOR PRODUCING BETA-ALANINE AMIDES | LONZA AG (CH) | 2010-12-29 | — | — | EP | claimed |
| US-7358393-B2 | Method for preparing β-alaninamides | LONZA LTD. (CH) | 2008-04-15 | — | — | US | claimed |
| US-20040220410-A1 | Method for preparing beta-alanine amides | LONZA AG (CH) | 2004-11-04 | — | — | US | claimed |
| EP-1430018-A1 | METHOD FOR PRODUCING BETA-ALANINE AMIDES | LONZA AG (CH) | 2004-06-23 | — | — | EP | claimed |
| WO-2003022795-A1 | METHOD FOR PRODUCING BETA-ALANINE AMIDES | LONZA AG (CH) | 2003-03-20 | — | — | WO | claimed |
| EP-1430018-B1 | METHOD FOR PRODUCING BETA-ALANINE AMIDES | LONZA AG (CH) | 2010-12-29 | — | — | EP | disclosed |
| EP-1430018-B1 | METHOD FOR PRODUCING BETA-ALANINE AMIDES | LONZA AG (CH) | 2010-12-29 | — | — | EP | disclosed |
| US-7358393-B2 | Method for preparing β-alaninamides | LONZA LTD. (CH) | 2008-04-15 | — | — | US | disclosed |
| US-7358393-B2 | Method for preparing β-alaninamides | LONZA LTD. (CH) | 2008-04-15 | — | — | US | disclosed |
| US-7358393-B2 | Method for preparing β-alaninamides | LONZA LTD. (CH) | 2008-04-15 | — | — | US | disclosed |
| US-20040220410-A1 | Method for preparing beta-alanine amides | LONZA AG (CH) | 2004-11-04 | — | — | US | disclosed |
| EP-1430018-A1 | METHOD FOR PRODUCING BETA-ALANINE AMIDES | LONZA AG (CH) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003022795-A1 | METHOD FOR PRODUCING BETA-ALANINE AMIDES | LONZA AG (CH) | 2003-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220410-A1 | Method for preparing beta-alanine amides | HNMT, AADAT, HRH3 | MCL1 3004/4885NAMPT 2172/4885F10 2638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.