SCHEMBL4393206

SCHEMBL4393206

CCOC(=O)Oc1ccccc1C(=O)Oc1ccccc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
HSD17B10 Q99714 4/20 0.49
KDM4E B2RXH2 3/20 0.49
LMNA P02545 2/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2C9 P11712 2/20 0.49
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
SLC6A3 Q01959 1/20 0.45
PKM P14618 1/20 0.45
ALDH1A1 P00352 3/20 0.44
HPGD P15428 2/20 0.44
PTGS2 P35354 1/20 0.44
TDP1 Q9NUW8 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ATM Q13315 1/20 0.43
GAA P10253 2/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4397337 0.89 TSHR (0.61) TSHRHSD17B10KDM4ELMNACYP1A2
SCHEMBL4394455 0.89 HSD17B10 (0.56) TSHRHSD17B10KDM4ELMNACYP1A2
SCHEMBL1598707 0.89 TDP1 (0.51) TSHRLMNAALDH1A1TDP1L3MBTL1
SCHEMBL4391361 0.87 TSHR (0.67) TSHRHSD17B10KDM4ELMNACYP1A2
SCHEMBL1914150 0.86 TSHR (0.55) TSHRHSD17B10KDM4ELMNACYP1A2
SCHEMBL5706067 0.86 TSHR (0.65) TSHRHSD17B10KDM4ELMNACYP1A2
SCHEMBL4385296 0.85 HSD17B10 (0.54) TSHRHSD17B10KDM4ELMNACYP1A2
SCHEMBL4391331 0.84 SLC6A3 (0.59) TSHRHSD17B10KDM4ELMNAKMT2A
SCHEMBL4392105 0.84 ESR1 (0.54) TSHRHSD17B10KDM4ELMNACYP1A2
SCHEMBL12196045 0.84 TSHR (0.53) TSHRHSD17B10KDM4ELMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829854-B1 PROCESS FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2013-09-04 EP disclosed
US-7629485-B2 Process for producing aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-12-08 US disclosed
US-20080177099-A1 Process for Producing Aromatic Carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2008-07-24 US disclosed
EP-1829854-A1 PROCESS FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2007-09-05 EP disclosed
EP-1016648-B1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES ASAHI CHEMICAL IND (JP) 2003-05-14 EP disclosed
US-6262210-B1 TRANSESTERIFYING DIALKYL CARBONATE, ALKYL ARYL CARBONATE OR MIXTURE WITH AROMATIC MONOHYDROXY COMPOUND IN PRESENCE OF METAL CONTAINING CATALYST TO OBTAIN HIGH BOILING POINT REACTION MIXTURE CONTAINING AROMATIC CARBONATE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-07-17 US disclosed
EP-1016648-A1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080177099-A1 Process for Producing Aromatic Carbonate DCLK1, ALK, DCLK3 TSHR 4099/4885HSD17B10 963/4885KDM4E 481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.