SCHEMBL4385296

SCHEMBL4385296

CCOC(=O)Oc1ccccc1C(=O)Oc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 6/20 0.54
ALDH1A1 P00352 4/20 0.54
TSHR P16473 3/20 0.54
KMT2A Q03164 1/20 0.54
CYP1A2 P05177 3/20 0.52
CYP2C9 P11712 3/20 0.52
CYP2C19 P33261 2/20 0.52
MAPT P10636 4/20 0.51
KDM4E B2RXH2 3/20 0.51
TDP1 Q9NUW8 1/20 0.51
HPGD P15428 4/20 0.50
ALOX15 P16050 2/20 0.50
LMNA P02545 2/20 0.50
PTGS2 P35354 1/20 0.50
CYP2D6 P10635 1/20 0.49
MAPK1 P28482 1/20 0.49
CASP3 P42574 1/20 0.49
RAB9A P51151 1/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP7 Q9BQF6 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4393205 0.91 PTK2B (0.52) HSD17B10ALDH1A1TSHRKMT2ACYP1A2
SCHEMBL1282822 0.88 TSHR (0.59) HSD17B10ALDH1A1TSHRKMT2ACYP1A2
SCHEMBL4391361 0.87 TSHR (0.67) HSD17B10ALDH1A1TSHRKMT2ACYP1A2
SCHEMBL4389489 0.86 HSD17B10 (0.55) HSD17B10ALDH1A1TSHRKMT2ACYP1A2
SCHEMBL1914150 0.86 TSHR (0.55) HSD17B10ALDH1A1TSHRKMT2ACYP1A2
SCHEMBL1282647 0.85 HSD17B10 (0.64) HSD17B10ALDH1A1TSHRKMT2ACYP1A2
SCHEMBL4393206 0.85 TSHR (0.50) HSD17B10ALDH1A1TSHRKMT2ACYP1A2
SCHEMBL5706140 0.85 TSHR (0.56) HSD17B10ALDH1A1TSHRKMT2AMAPT
SCHEMBL4391331 0.84 SLC6A3 (0.59) HSD17B10ALDH1A1TSHRKMT2AMAPT
SCHEMBL12196045 0.84 TSHR (0.53) HSD17B10ALDH1A1TSHRKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829854-B1 PROCESS FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2013-09-04 EP disclosed
US-7629485-B2 Process for producing aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-12-08 US disclosed
US-20080177099-A1 Process for Producing Aromatic Carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2008-07-24 US disclosed
EP-1829854-A1 PROCESS FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2007-09-05 EP disclosed
EP-1016648-B1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES ASAHI CHEMICAL IND (JP) 2003-05-14 EP disclosed
US-6262210-B1 TRANSESTERIFYING DIALKYL CARBONATE, ALKYL ARYL CARBONATE OR MIXTURE WITH AROMATIC MONOHYDROXY COMPOUND IN PRESENCE OF METAL CONTAINING CATALYST TO OBTAIN HIGH BOILING POINT REACTION MIXTURE CONTAINING AROMATIC CARBONATE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-07-17 US disclosed
EP-1016648-A1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080177099-A1 Process for Producing Aromatic Carbonate DCLK1, ALK, DCLK3 HSD17B10 963/4885ALDH1A1 1791/4885TSHR 4099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.