Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593661 | 0.79 | PNMT (0.39) | PNMTNPC1RAB9AHTR7HTR2B | |
| Fluorene SCHEMBL22289755 | 0.74 | MAOA (0.54) | PNMTNPC1RAB9AHTR2BKDM4E | |
| Hydrochloric Acid SCHEMBL3385861 | 0.73 | PNMT (0.52) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL30274953 | 0.73 | PNMT (0.52) | PNMTNPC1RAB9AHTR7HTR2B | |
| Iodide SCHEMBL3382482 | 0.73 | PNMT (0.52) | PNMTNPC1RAB9AHTR7HTR2B | |
| Fluoride Ion SCHEMBL3384402 | 0.73 | PNMT (0.52) | PNMTNPC1RAB9AHTR7HTR2B | |
| Bromide SCHEMBL3383744 | 0.73 | PNMT (0.52) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL524602 | 0.72 | PNMT (0.63) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL30103334 | 0.72 | PNMT (0.63) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL8984790 | 0.71 | PNMT (0.46) | PNMTNPC1RAB9AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101215370-B | Substituted fluorene polymers, their preparations and use in optical devices | CAMBRIDGE DISPLAY TECH LTD | 2012-06-20 | — | — | CN | disclosed |
| US-7632908-B2 | Substituted fluorene polymers, their preparation and use in optical devices | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2009-12-15 | — | — | US | disclosed |
| CN-100417703-C | Substituted fluorene polymers, their preparation and use in optical devices | CAMBRIDGE DISPLAY TECH LTD (GB) | 2008-09-10 | — | — | CN | disclosed |
| CN-101215370-A | Substituted fluorene polymers, their preparations and use in optical devices | CAMBRIDGE DISPLAY TECH LTD (GB) | 2008-07-09 | — | — | CN | disclosed |
| EP-1586617-A1 | Substituted fluorene polymers, their preparations and use in optical devices | Cambridge Display Technology Limited (GB) | 2005-10-19 | — | — | EP | disclosed |
| US-20040170839-A1 | Substituted fluorenes polymers, their preparation and use in optical devices | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2004-09-02 | — | — | US | disclosed |
| CN-1513044-A | Substituted fluorene polymers, their preparation and use in optical devices | ʾ | 2004-07-14 | — | — | CN | disclosed |
| EP-1385918-A1 | SUBSTITUTED FLUORENE POLYMERS, THEIR PREPARATION AND USE IN OPTICAL DEVICES | Cambridge Display Technology Limited (GB) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002092723-A1 | SUBSTITUTED FLUORENE POLYMERS, THEIR PREPARATION AND USE IN OPTICAL DEVICES | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2002-11-21 | — | — | WO | disclosed |