SCHEMBL4393909

SCHEMBL4393909

CCOc1cc(O)ccc1CN

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
KMT2A Q03164 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
GAA P10253 1/20 0.41
THRB P10828 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
ATM Q13315 1/20 0.41
PLEC Q15149 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
LTA4H P09960 1/20 0.40
CAPN1 P07384 1/20 0.39
CTSL P07711 1/20 0.39
CTSB P07858 1/20 0.39
AOC3 Q16853 2/20 0.39
HSD17B10 Q99714 2/20 0.39
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1049677 0.86 HTR2C (0.41) MAPTRECQLCALM1MAOB
SCHEMBL4399572 0.86 CSNK2A1 (0.45) ALDH1A1MEN1MAPTKMT2AL3MBTL1
SCHEMBL4449940 0.81 TYR (0.46) MEN1MAPTKMT2ATDP1CALM1
SCHEMBL28282872 0.81 ALDH1A1 (0.41) ALDH1A1MEN1MAPTKMT2AL3MBTL1
SCHEMBL772479 0.81 MAOB (0.55) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL28480661 0.80 KMT2A (0.40) ALDH1A1MEN1MAPTKMT2AL3MBTL1
Hydrochloric Acid SCHEMBL742117 0.79 MAOB (0.53) MEN1MAPTKMT2AGAAMAPK1
SCHEMBL4618673 0.79 KDM4E (0.53) ALDH1A1MEN1MAPTKMT2AL3MBTL1
SCHEMBL8147933 0.79 TYR (0.61) MEN1MAPTKMT2ATDP1TYR
SCHEMBL3026188 0.78 CALM1 (0.51) ALDH1A1MEN1MAPTKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8227390-B2 Binder resin for friction material, binder resin composition for friction material, composite material for friction material containing the same, friction material and production method thereof AKEBONO BRAKE INDUSTRY CO., LTD. (JP) 2012-07-24 US disclosed
US-20090137434-A1 BINDER RESIN FOR FRICTION MATERIAL, BINDER RESIN COMPOSITION FOR FRICTION MATERIAL, COMPOSITE MATERIAL FOR FRICTION MATERIAL CONTAINING THE SAME, FRICTION MATERIAL AND PRODUCTION METHOD THEREOF AKEBONO BRAKE INDUSTRY CO., LTD (JP) 2009-05-28 US disclosed