SCHEMBL4393987

SCHEMBL4393987

C=CC(=O)O[SiH](CCC)OCC

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.41
HPGD P15428 1/20 0.41
THRB P10828 3/20 0.35
ALDH1A1 P00352 4/20 0.32
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7766210 0.88 TSHR (0.47) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL4394880 0.82 TSHR (0.42) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL5946696 0.81
SCHEMBL4357212 0.78 TSHR (0.43) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL3748229 0.78 TSHR (0.40) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL28618494 0.78 TSHR (0.41) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL28253738 0.77 TSHR (0.51) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL29156652 0.76 TSHR (0.39) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL21879730 0.76 TSHR (0.44) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL11143543 0.76 TSHR (0.44) TSHRHPGDTHRBALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 310 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110508222-A Monodisperse core-shell particles and preparation method thereof with mesoporous silicon oxide shell UNIV FUDAN 2019-11-29 CN claimed
CN-110392708-A Adhesive composition based on graft resin 洛德公司 2019-10-29 CN claimed
CN-109843229-A By the pinpoint accuracy drug delivery of dual domain device for eyes 领视药公司 2019-06-04 CN claimed
CN-109820279-A A kind of preparation method of the antifreeze foot warming shoe of waterproof 浙江太极鞋业有限公司 2019-05-31 CN claimed
CN-109793312-A A kind of preparation method of health care playshoes 浙江太极鞋业有限公司 2019-05-24 CN claimed
CN-109790243-A Three block prepolymer and its purposes in silicone hydrogels 庄臣及庄臣视力保护公司 2019-05-21 CN claimed
CN-109749029-A A kind of high molecular polymer and preparation method and application 兰州理工大学 2019-05-14 CN claimed
CN-109730402-A A kind of playshoes and preparation method with double-purpose functional 浙江太极鞋业有限公司 2019-05-10 CN claimed
CN-107304051-B A kind of inorganic nano Porous materials and preparation method thereof 中国科学院化学研究所 2019-03-26 CN claimed
CN-109476824-A Bi-component plaster material and application thereof 喜利得股份公司 2019-03-15 CN claimed
CN-104114611-B Silicone hydrogels comprising N-vinylamides and hydroxyalkyl (meth) acrylates or (meth) acrylamides 庄臣及庄臣视力保护公司 2016-11-16 CN claimed
CN-105949921-A Modified epoxy acrylate heatproof and ultraviolet resistant paint for building exterior walls 梁冬 2016-09-21 CN claimed
CN-105153352-A Inorganic modified acrylic resin and preparation method thereof as well as cement prefabricated part SHENZHEN JIADA HIGH TECH INDUSTRY DEV CO LTD 2015-12-16 CN claimed
CN-105164555-A Primary amine-containing silicone hydrogel contact lenses and related compositions and methods COOPERVISION INT HOLDING CO LP 2015-12-16 CN claimed
CN-105074506-A Silicone-containing contact lens having clay treatment applied thereto JOHNSON & JOHNSON VISION CARE 2015-11-18 CN claimed
CN-105008115-A Silicone-containing contact lens having reduced amount of silicon on the surface JOHNSON & JOHNSON VISION CARE 2015-10-28 CN claimed
CN-104640894-A Two-component polyurethane composition SIKA TECHNOLOGY AG 2015-05-20 CN claimed
CN-102219439-B Chemical two component mortar composition with improved adhesion to the surface of semi-purified and/or wet bore holes in mineral base and use of same HILTI AG 2015-03-25 CN claimed
CN-104379330-A Lens comprising low molecular weight polyamide and high molecular weight polyamide JOHNSON & JOHNSON VISION CARE 2015-02-25 CN claimed
CN-102171589-B Ionic silicone hydrogels having improved hydrolytic stability JOHNSON & JOHNSON VISION CARE 2015-01-14 CN claimed