SCHEMBL4394880

SCHEMBL4394880

C=CC(=O)O[SiH](CCC)OC

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.42
HPGD P15428 1/20 0.42
THRB P10828 4/20 0.36
ALDH1A1 P00352 5/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
THRA P10827 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7766210 0.90 TSHR (0.47) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL3748229 0.83 TSHR (0.40) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL4393987 0.82 TSHR (0.41) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL4419862 0.81 ATM (0.31)
SCHEMBL4357212 0.79 TSHR (0.43) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL11143543 0.78 TSHR (0.44) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL21879730 0.78 TSHR (0.44) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL29171161 0.77 TSHR (0.57) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL524128 0.74 ALDH1A1 (0.41) TSHRTHRBALDH1A1
SCHEMBL584640 0.74 TSHR (0.38) TSHRHPGDTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3954274-A Clay tile pipe joint seal containing foamed unsaturated polyester resin FREEMAN CHEMICAL CORPORATION (US) 1976-05-04 US claimed
WO-2025053279-A1 ORGANOPOLYSILOXANE, ORGANOPOLYSILOXANE-CONTAINING RESIN COMPOSITION, CURED PRODUCT THEREOF, ORGANOPOLYSILOXANE FOR NEAR-INFRARED OPTICAL WAVEGUIDE, ORGANOPOLYSILOXANE-CONTAINING RESIN COMPOSITION FOR NEAR-INFRARED OPTICAL WAVEGUIDE, CURED PRODUCT FOR NEAR-INFRARED OPTICAL WAVEGUIDE, NEAR-INFRARED OPTICAL WAVEGUIDE, NEAR-INFRARED OPTICAL TRANSMISSION MEMBER, AND NEAR-INFRARED OPTICAL WAVEGUIDE PRODUCTION METHOD 三菱ケミカル株式会社 2025-03-13 WO disclosed
WO-2025053278-A1 ORGANOPOLYSILOXANE, ORGANOPOLYSILOXANE COMPOSITION, CURED PRODUCT THEREOF, ORGANOPOLYSILOXANE FOR NEAR-INFRARED OPTICAL WAVEGUIDE, ORGANOPOLYSILOXANE COMPOSITION FOR NEAR-INFRARED OPTICAL WAVEGUIDE, CURED PRODUCT FOR NEAR-INFRARED OPTICAL WAVEGUIDE, NEAR-INFRARED OPTICAL WAVEGUIDE, NEAR-INFRARED OPTICAL TRANSMISSION MEMBER, AND NEAR-INFRARED OPTICAL WAVEGUIDE PRODUCTION METHOD 三菱ケミカル株式会社 2025-03-13 WO disclosed
WO-2025053280-A1 OPTICAL WAVEGUIDE AND OPTICAL MEMBER HAVING OPTICAL WAVEGUIDE 三菱ケミカル株式会社 2025-03-13 WO disclosed
CN-108333869-B Photosensitive composition, cured film, method for producing same, and display element, light-emitting element, and light-receiving element JSR株式会社 2023-07-18 CN disclosed
CN-115141551-A Adhesive sheet 索马龙株式会社 2022-10-04 CN disclosed
CN-114450369-A Adhesive sheet 王子控股株式会社 2022-05-06 CN disclosed
CN-110167981-B Copolymer and resin composition 株式会社日本触媒 2022-04-08 CN disclosed
WO-2021066036-A1 PRESSURE-SENSITIVE ADHESIVE SHEET 王子ホールディングス株式会社 2021-04-08 WO disclosed
WO-2021066037-A1 ADHESIVE SHEET AND METHOD FOR MANUFACTURING ADHESIVE SHEET 王子ホールディングス株式会社 2021-04-08 WO disclosed
US-10082605-B2 Manufacturing method of antireflection article, antireflection article, cover glass, and image display device FUJIFILM CORPORATION (JP) 2018-09-25 US disclosed
US-20160299260-A1 MANUFACTURING METHOD OF ANTIREFLECTION ARTICLE, ANTIREFLECTION ARTICLE, COVER GLASS, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-13 US disclosed
EP-1539862-B1 COMPOSITION ACTING AS COUPLING AGENT FOR FILLED AND PEROXIDICALLY CROSSLINKING RUBBER COMPOUNDS EVONIK DEGUSSA GMBH (DE) 2009-12-09 EP disclosed
US-7625975-B2 Composition acting as coupling agent for filled and peroxidically crosslinking rubber compounds DEGUSSA AG (DE) 2009-12-01 US disclosed
US-7405244-B2 Solvent-free polyimide silicone resin composition and a resin film composed of the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-07-29 US disclosed
US-20070177271-A1 Antireflection film, polarizing plate and image display FUJIFILM CORPORATION (JP) 2007-08-02 US disclosed
US-20070032609-A1 Composition acting as coupling agent for filled and peroxidically crosslinking rubber compounds DEGUSSA AG (DE) 2007-02-08 US disclosed
US-20060084714-A1 Solvent-free polyimide silicone resin composition and a resin film composed of the same SHIN-ETSU CHEMICAL CO., LTD. (US) 2006-04-20 US disclosed
EP-1539862-A1 COMPOSITION ACTING AS COUPLING AGENT FOR FILLED AND PEROXIDICALLY CROSSLINKING RUBBER COMPOUNDS Degussa AG (DE) 2005-06-15 EP disclosed
WO-2004018546-A1 COMPOSITION ACTING AS COUPLING AGENT FOR FILLED AND PEROXIDICALLY CROSSLINKING RUBBER COMPOUNDS DEGUSSA AG (DE) 2004-03-04 WO disclosed