Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21859055 | 0.85 | DGAT1 (0.41) | DGAT1PDE10A | |
| SCHEMBL4394992 | 0.84 | DGAT1 (0.43) | DGAT1PDE10A | |
| SCHEMBL27858492 | 0.77 | DGAT1 (0.36) | DGAT1PDE10A | |
| SCHEMBL2114061 | 0.77 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL23208935 | 0.75 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL31748468 | 0.75 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL30461589 | 0.74 | MTNR1A (0.37) | DGAT1PDE10A | |
| SCHEMBL31118749 | 0.74 | DGAT1 (0.36) | DGAT1PDE10A | |
| SCHEMBL25420978 | 0.74 | MTNR1A (0.37) | DGAT1PDE10A | |
| SCHEMBL26912892 | 0.74 | DGAT1 (0.34) | DGAT1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2056822-A1 | SUBSTITUTED PYRROLOPYRIDINES AND PYRAZOLOPYRIDINES AS KINASE MODULATORS | SGX Pharmaceuticals, Inc. (US) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008150914-A1 | SUBSTITUTED PYRROLOPYRIDINES AND PYRAZOLOPYRIDINES AS KINASE MODULATORS | SGX PHARMACEUTICALS, INC. (US) | 2008-12-11 | — | — | WO | disclosed |