Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3157167 | 0.85 | HTR6 (0.60) | MCOLN3HTR6ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3144083 | 0.75 | HTR6 (0.62) | MCOLN3HTR6ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4397950 | 0.74 | KMT2A (0.47) | HTR6ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL3153809 | 0.74 | HTR6 (0.68) | HTR6ALDH1A1LMNAL3MBTL1NPC1 | |
| SCHEMBL3142768 | 0.74 | HTR6 (0.48) | MCOLN3HTR6ALDH1A1SMN1; SMN2 | |
| SCHEMBL3153499 | 0.74 | HTR6 (0.46) | MCOLN3HTR6ALDH1A1MAPTCYP3A4 | |
| SCHEMBL3153379 | 0.74 | MCOLN3 (0.54) | MCOLN3HTR6ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL3148785 | 0.73 | HTR6 (0.59) | HTR6ALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL3147451 | 0.73 | HTR6 (0.56) | MCOLN3HTR6MAPK1SMN1; SMN2LMNA | |
| SCHEMBL5430834 | 0.72 | DHCR7 (0.48) | HTR6ALDH1A1CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-B1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2009-12-09 | — | — | EP | claimed |