Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTR6 | P50406 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3144297 | 0.84 | HTR6 (0.65) | KMT2AMEN1ALDH1A1HTR6 | |
| SCHEMBL5430834 | 0.78 | DHCR7 (0.48) | KMT2AALDH1A1HTR6KDM4E | |
| SCHEMBL3152556 | 0.76 | HTR6 (0.56) | KMT2AMEN1ALDH1A1HTR6 | |
| SCHEMBL3143063 | 0.75 | HTR6 (0.64) | HTR6 | |
| SCHEMBL4394633 | 0.74 | MCOLN3 (0.43) | ALDH1A1HTR6LMNASMN1; SMN2MAPT | |
| SCHEMBL13809475 | 0.73 | HTR6 (0.52) | KMT2AMEN1ALDH1A1HTR6 | |
| SCHEMBL3148297 | 0.73 | HTR6 (0.66) | KMT2AMEN1ALDH1A1HTR6LMNA | |
| SCHEMBL3155757 | 0.73 | HTR6 (0.55) | KMT2AMEN1ALDH1A1HTR6MAPT | |
| SCHEMBL3142983 | 0.73 | HTR6 (0.51) | KMT2AMEN1ALDH1A1HTR6 | |
| SCHEMBL3143802 | 0.72 | HTR6 (0.63) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-B1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2009-12-09 | — | — | EP | claimed |