Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.45 |
| ▸ | CDK1 | P06493 | 6/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | MGMT | P16455 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29693584 | 0.88 | CDK2 (0.41) | CDK2CDK1CDK4CCNA2CCNA1 | |
| SCHEMBL2745214 | 0.88 | CDK2 (0.41) | CDK2CDK1CDK4CCNA2CCNA1 | |
| SCHEMBL9443788 | 0.87 | CDK2 (0.47) | CDK2CDK1CDK4CCNA2CCNA1 | |
| SCHEMBL9443855 | 0.80 | CDK2 (0.33) | CDK2CDK1CDK4CCNA2CCNA1 | |
| SCHEMBL439475 | 0.78 | CDK2 (0.61) | CDK2CDK1CDK4CCNA2CCNA1 | |
| SCHEMBL9443860 | 0.74 | CDK2 (0.32) | CDK2CDK1CDK4CCNA2CCNA1 | |
| SCHEMBL7767432 | 0.74 | CDK2 (0.45) | CDK2CDK1CDK4CCNA2CCNA1 | |
| SCHEMBL4160357 | 0.73 | CDK2 (0.52) | CDK2CDK1CDK4CCNA2CCNA1 | |
| SCHEMBL29473573 | 0.73 | CDK2 (0.52) | CDK2CDK1CDK4CCNA2CCNA1 | |
| SCHEMBL11073630 | 0.72 | HSP90AA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001089587-A2 | AGENTS FOR DYEING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-11-29 | — | — | WO | claimed |
| US-5213972-A | Production of thymidine and deoxyuridine, intermediates for AZT | CHEMGEN CORPORATION (US) | 1993-05-25 | — | — | US | disclosed |