SCHEMBL4160357

SCHEMBL4160357

Nc1nc(N)c(N=O)c(O)n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 7/20 0.52
CCNA2 P20248 6/20 0.52
CCNA1 P78396 6/20 0.52
CDK1 P06493 6/20 0.41
CCNB1 P14635 5/20 0.41
MGMT P16455 3/20 0.41
CDK4 P11802 1/20 0.41
KMT2A Q03164 3/20 0.41
MAPT P10636 2/20 0.41
POLB P06746 1/20 0.41
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MEN1 O00255 2/20 0.39
CCNB2 O95067 1/20 0.39
MTOR P42345 1/20 0.39
ATR Q13535 1/20 0.39
CCNB3 Q8WWL7 1/20 0.39
CYP1A2 P05177 3/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29473573 1.00 CDK2 (0.52) CDK2CCNA2CCNA1CDK1CCNB1
Nitrous Acid SCHEMBL29168822 0.96 CDK2 (0.48) CDK2CCNA2CCNA1CDK1CCNB1
Nitrous Acid SCHEMBL28603506 0.92 CDK2 (0.46) CDK2CCNA2CCNA1CDK1CCNB1
SCHEMBL7766478 0.88 CDK2 (0.42) CDK2CCNA2CCNA1CDK1CCNB1
SCHEMBL439475 0.83 CDK2 (0.61) CDK2CCNA2CCNA1CDK1CCNB1
SCHEMBL29693584 0.82 CDK2 (0.41) CDK2CCNA2CCNA1CDK1CCNB1
SCHEMBL2745214 0.82 CDK2 (0.41) CDK2CCNA2CCNA1CDK1CCNB1
SCHEMBL10441417 0.78 CDK2 (0.38) CDK2CCNA2CCNA1CDK1CDK4
SCHEMBL5026853 0.78 CDK2 (0.38) CDK2CCNA2CCNA1CDK1CDK4
SCHEMBL6402248 0.78 CDK2 (0.40) CDK2CCNA2CCNA1CDK1CCNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026097624-A1 METHOD FOR PREPARING CHLORINE-RESISTANT NANOFILTRATION MEMBRANE, AND CHLORINE-RESISTANT NANOFILTRATION MEMBRANE PREPARED THEREWITH 沃顿科技股份有限公司 2026-05-15 WO claimed
WO-2024092895-A1 METHOD FOR PREPARING 2,4,5-TRIAMINO-6-HYDROXYPYRIMIDINE SULFATE BY MEANS OF MICRO-CHANNEL REACTION 南通市常海食品添加剂有限公司 2024-05-10 WO claimed
CN-117430608-A Guanine synthesis method 湖北益泰药业股份有限公司 2024-01-23 CN claimed
CN-115286584-B Preparation method of 2,4, 5-triamino-6-hydroxypyrimidine sulfate 宁波丰谊实业有限公司 2023-12-26 CN claimed
CN-116272334-B Coupling desulfurization and denitrification medicament, preparation method and use method thereof 杭州尚善若水环保科技有限公司 2023-08-15 CN claimed
CN-116272334-A Coupling desulfurization and denitrification medicament, preparation method and use method thereof 杭州尚善若水环保科技有限公司 2023-06-23 CN claimed
CN-114380832-B One-step synthesis method of guanine 湖北李泽园医药科技有限公司 2023-06-16 CN claimed
CN-111646994-B Preparation method and application of 2, 4-diamino-6-hydroxy-5-formamido pyrimidine 潍坊奥通药业有限公司 2023-04-18 CN claimed
CN-115650922-A Method for preparing 2,4,5-triamino-6-hydroxypyrimidine sulfate through microchannel reaction 南通市常海食品添加剂有限公司 2023-01-31 CN claimed
CN-115286584-A Preparation method of 2,4, 5-triamino-6-hydroxypyrimidine sulfate 宁波丰谊实业有限公司 2022-11-04 CN claimed
WO-2001089587-A2 AGENTS FOR DYEING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-11-29 WO claimed
US-5648490-A Process for the preparation of 5-formylaminopyrimidines SKW TROSTBERG AKTIENGESELLSCHAFT (DE) 1997-07-15 US claimed
EP-0675113-A2 Process for the preparation of 5-formylaminopyrimidines SKW Trostberg Aktiengesellschaft (DE) 1995-10-04 EP claimed
EP-0444266-B1 Process for the preparation of 2,4,5-triamino-6-hydroxypyrimidine by catalytic hydrogenation of 2,4-diamino-6-hydroxy-5-nitrosopyrimidine HUELS CHEMISCHE WERKE AG (DE) 1995-02-15 EP claimed
EP-0267594-B1 METHOD FOR THE CATALYTIC HYDROGENATION OF DAHNP AND FOR PREPARING DAFHP BOEHRINGER INGELHEIM KG (DE) 1993-02-10 EP claimed
US-5101031-A PREPARATION OF 2,4,5-TRIAMINO-6-HYDROXYPYRIMIDINE BY CATALYTIC HYDROGENATION OF 2,4-DIAMINO-6-HYDROXY-5-NITROSO-PYRIMIDINE HUELS AKTIENGESELLSCHAFT (DE) 1992-03-31 US claimed
EP-0444266-A1 Process for the preparation of 2,4,5-triamino-6-hydroxypyrimidine by catalytic hydrogenation of 2,4-diamino-6-hydroxy-5-nitrosopyrimidine HÜLS AKTIENGESELLSCHAFT (DE) 1991-09-04 EP claimed
US-4948890-A Process for the preparation of DAFNP BOEHRINGER INGELHEIM KG (DE) 1990-08-14 US claimed
US-4868302-A Process for the preparation of TAHP BOEHRINGER INGELHEIM KG (DE) 1989-09-19 US claimed
EP-0267594-A1 Method for the catalytic hydrogenation of DAHNP and for preparing DAFHP BOEHRINGER INGELHEIM KG (DE) 1988-05-18 EP claimed