Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FBP1 | P09467 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3813362 | 0.78 | ALDH1A1 (0.40) | TDP1FBP1POLBMEN1KMT2A | |
| SCHEMBL6770368 | 0.73 | TDP1 (0.46) | TDP1FBP1POLBMEN1KMT2A | |
| SCHEMBL17224000 | 0.73 | TDP1 (0.42) | TDP1FBP1POLBMEN1KMT2A | |
| SCHEMBL14352772 | 0.71 | TDP1 (0.50) | TDP1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL28966398 | 0.71 | TDP1 (0.50) | TDP1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL30304769 | 0.71 | TDP1 (0.50) | TDP1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL1694355 | 0.70 | ALDH1A1 (0.48) | TDP1MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8392625 | 0.68 | TDP1 (0.50) | TDP1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL11213482 | 0.68 | TDP1 (0.50) | TDP1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL1856414 | 0.67 | ALDH1A1 (0.50) | TDP1POLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123159-A1 | (1,2-Benzisothiazol-3-yl)(thio)carbamates and (1,2-Benzisothiazol-3-yl)(thio)oxamates and their oxidation forms as pesticides | Bayer CropScience AG (DE) | 2009-11-25 | — | — | EP | disclosed |