Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508386 | 0.91 | KMO (0.46) | NOTUMALDH1A1ALOX15SLC6A2SLC6A4 | |
| SCHEMBL28140772 | 0.91 | KMO (0.46) | NOTUMALDH1A1ALOX15SLC6A2SLC6A4 | |
| SCHEMBL1500383 | 0.88 | ALDH1A1 (0.50) | NOTUMALDH1A1ALOX15SLC6A2SLC6A4 | |
| SCHEMBL4109572 | 0.82 | ALDH1A1 (0.54) | NOTUMALDH1A1ALOX15CYP2C9POLB | |
| SCHEMBL30175300 | 0.82 | ALDH1A1 (0.54) | NOTUMALDH1A1ALOX15CYP2C9POLB | |
| SCHEMBL10457353 | 0.82 | ALDH1A1 (0.54) | NOTUMALDH1A1ALOX15CYP2C9POLB | |
| SCHEMBL28034437 | 0.81 | ALDH1A1 (0.50) | NOTUMALDH1A1ALOX15CYP2C9POLB | |
| SCHEMBL30689750 | 0.81 | ALDH1A1 (0.50) | NOTUMALDH1A1ALOX15CYP2C9POLB | |
| Hydrochloric Acid SCHEMBL29705669 | 0.80 | ALDH1A1 (0.52) | NOTUMALDH1A1ALOX15CYP2C9POLB | |
| SCHEMBL3686998 | 0.79 | ALB (0.53) | NOTUMALDH1A1ALOX15SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009132453-A1 | CYCLYLAMINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2009-11-05 | — | — | WO | disclosed |