Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4386364 | 0.82 | TLR8 (0.33) | TLR8 | |
| SCHEMBL4390264 | 0.81 | POLB (0.41) | TLR8 | |
| SCHEMBL4389110 | 0.79 | TLR8 (0.42) | TLR8 | |
| SCHEMBL14368399 | 0.79 | DPP4 (0.37) | — | |
| SCHEMBL13591007 | 0.75 | — | — | |
| SCHEMBL4385722 | 0.75 | ALDH1A1 (0.30) | — | |
| SCHEMBL14394043 | 0.74 | ALDH1A1 (0.30) | — | |
| SCHEMBL13591031 | 0.73 | — | — | |
| SCHEMBL4393940 | 0.72 | LMNA (0.32) | TLR8 | |
| SCHEMBL14393963 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569922-B1 | 1,2,4-THIADIAZOLE COMPOUNDS AND ARTHROPOD CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2009-12-02 | — | — | EP | disclosed |
| US-7301032-B2 | 1,2,4-thiadiazole compounds and arthropod controlling composition containing the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2007-11-27 | — | — | US | disclosed |
| US-20060052422-A1 | 1,2,4-Thiadiazole compounds and arthropod controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-03-09 | — | — | US | disclosed |
| EP-1569922-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND ARTHROPOD CONTROLLING COMPOSITION CONTAINING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004046125-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND ARTHROPOD CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052422-A1 | 1,2,4-Thiadiazole compounds and arthropod controlling composition containing the same | NAT1, C1S, C1R | TLR8 4333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.