Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | RECQL | P46063 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | ALPL | P05186 | 1/20 | 0.68 |
| ▸ | ALPI | P09923 | 1/20 | 0.68 |
| ▸ | ALPG | P10696 | 1/20 | 0.68 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.68 |
| ▸ | CASP6 | P55212 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 10/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.49 |
| ▸ | MEN1 | O00255 | 9/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Acetylaminorhodanine SCHEMBL8000045 | 0.78 | MAPT (0.73) | MAPTALDH1A1RECQLPOLBKDM4E | |
| SCHEMBL10278696 | 0.74 | MAPT (0.67) | MAPTALDH1A1RECQLPOLBKDM4E | |
| SCHEMBL10278642 | 0.74 | MAPT (0.77) | MAPTALDH1A1RECQLPOLBKDM4E | |
| SCHEMBL6324088 | 0.74 | MAPT (0.67) | MAPTALDH1A1RECQLPOLBKDM4E | |
| SCHEMBL11873187 | 0.73 | MAPT (0.65) | MAPTALDH1A1RECQLPOLBKDM4E | |
| SCHEMBL11985604 | 0.72 | — | — | |
| N-Benzoylaminorhodanine SCHEMBL8595198 | 0.70 | MAPT (0.74) | MAPTALDH1A1RECQLPOLBKDM4E | |
| SCHEMBL302289 | 0.69 | MAPT (0.51) | MAPTALDH1A1RECQLPOLBKDM4E | |
| SCHEMBL8356860 | 0.68 | MAPT (1.00) | MAPTALDH1A1RECQLPOLBKDM4E | |
| SCHEMBL8224178 | 0.68 | MAPT (0.58) | MAPTALDH1A1RECQLPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117417746-A | Functional up-conversion nano probe for detecting chlorate with strong anti-interference and high sensitivity | 中国科学院新疆理化技术研究所 | 2024-01-19 | — | — | CN | claimed |
| US-20210349101-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. | 2021-11-11 | — | — | US | claimed |
| CN-113423698-A | Coumarin-based crosslinking agents | 文塔纳医疗系统公司 | 2021-09-21 | — | — | CN | claimed |
| EP-3853214-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | Ventana Medical Systems, Inc. (US) | 2021-07-28 | — | — | EP | claimed |
| WO-2020058339-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. (US) | 2020-03-26 | — | — | WO | claimed |
| EP-2588443-A2 | HAPTEN CONJUGATES FOR TARGET DETECTION | Ventana Medical Systems, Inc. (US) | 2013-05-08 | — | — | EP | claimed |
| US-20130109019-A1 | HAPTEN CONJUGATES FOR TARGET DETECTION | VENTANA MEDICAL SYSTEMS, INC. | 2013-05-02 | — | — | US | claimed |
| WO-2012003476-A2 | HAPTEN CONJUGATES FOR TARGET DETECTION | VENTANA MEDICAL SYSTEMS, INC. (US) | 2012-01-05 | — | — | WO | claimed |
| US-20240210288-A1 | Representative Diagnostics | VENTANA MED SYST INC (US) | 2024-06-27 | — | — | US | disclosed |
| US-11959838-B2 | Representative diagnostics | VENTANA MEDICAL SYSTEMS, INC. (US) | 2024-04-16 | — | — | US | disclosed |
| EP-4326736-A1 | MORPHOLOGICAL MARKER STAINING | Ventana Medical Systems, Inc. (US) | 2024-02-28 | — | — | EP | disclosed |
| US-20240043904-A1 | MORPHOLOGICAL MARKER STAINING | VENTANA MEDICAL SYSTEMS, INC. | 2024-02-08 | — | — | US | disclosed |
| CN-117417746-A | Functional up-conversion nano probe for detecting chlorate with strong anti-interference and high sensitivity | 中国科学院新疆理化技术研究所 | 2024-01-19 | — | — | CN | disclosed |
| CN-117417746-A | Functional up-conversion nano probe for detecting chlorate with strong anti-interference and high sensitivity | 中国科学院新疆理化技术研究所 | 2024-01-19 | — | — | CN | disclosed |
| EP-2078197-A2 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | Ventana Medical Systems, Inc. (US) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008153744-A2 | POLYMERIC CARRIERS FOR IMMUNOHISTOCHEMISTRY AND IN SITU HYBRIDIZATION | VENTANA MEDICAL SYSTEMS, INC. (US) | 2008-12-18 | — | — | WO | disclosed |
| US-20080305497-A1 | Polymeric carriers for immunohistochemistry and in situ hybridization | VENTANA MEDICAL SYSTEMS, INC. | 2008-12-11 | — | — | US | disclosed |
| US-20080268462-A1 | Derivatives containing oxazole, pyrazole, thiazole, nitroaryl compound, benzofurazan, triterpene, urea, thiourea, rotenoid, coumarin or cyclolignan such as 4-(2-hydroxyphenyl)-1H-benzo[b][1,4]diazepine-2(3H)-one; multiplexed diagnostic assay for multiple targets in sample; antibodies; kits | VENTANA MEDICAL SYSTEMS, INC. | 2008-10-30 | — | — | US | disclosed |
| WO-2008063378-A9 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | VENTANA MED SYST INC (US) | 2008-07-31 | — | — | WO | disclosed |
| WO-2008063378-A2 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | VENTANA MEDICAL SYSTEMS, INC. (US) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080268462-A1 | Derivatives containing oxazole, pyrazole, thiazole, nitroaryl compound, benzofurazan, triterpene, urea, thiourea, rotenoid, coumarin or cyclolignan such as 4-(2-hydroxyphenyl)-1H-benzo[b][1,4]diazepine-2(3H)-one; multiplexed diagnostic assay for multiple targets in sample; antibodies; kits | HRH4, CRBN, NCDN | MAPT 3454/4885ALDH1A1 2096/4885RECQL 2925/4885 |
| US-20130109019-A1 | HAPTEN CONJUGATES FOR TARGET DETECTION | TYR, TH, TYRO3 | MAPT 4799/4885ALDH1A1 1205/4885RECQL 1782/4885 |
| US-20080305497-A1 | Polymeric carriers for immunohistochemistry and in situ hybridization | FCGR2A, CD68, CA14 | MAPT 4554/4885ALDH1A1 180/4885RECQL 3974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.