Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | RECQL | P46063 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | GSK3A | P49840 | 7/20 | 0.46 |
| ▸ | GSK3B | P49841 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 10/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28604051 | 0.74 | MAPT (0.50) | MAPTALDH1A1RECQLTDP1POLB | |
| SCHEMBL28459177 | 0.71 | GSK3A (0.42) | MAPTALDH1A1RECQLTDP1POLB | |
| SCHEMBL23930054 | 0.71 | — | — | |
| SCHEMBL11985604 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL7533652 | 0.69 | GSK3A (0.56) | MAPTALDH1A1RECQLTDP1POLB | |
| SCHEMBL28470735 | 0.67 | MAPT (0.43) | MAPTALDH1A1RECQLTDP1POLB | |
| SCHEMBL3794356 | 0.67 | MEN1 (0.65) | MAPTALDH1A1RECQLTDP1POLB | |
| SCHEMBL3062340 | 0.66 | GSK3A (0.62) | MAPTALDH1A1RECQLTDP1POLB | |
| SCHEMBL6324088 | 0.66 | MAPT (0.67) | MAPTALDH1A1RECQLTDP1POLB | |
| N-Acetylaminorhodanine SCHEMBL8000045 | 0.66 | MAPT (0.73) | MAPTALDH1A1RECQLTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110229165-B | Up-conversion fluorescent probe rhodamine derivative and application thereof | 苏州科技大学 | 2020-11-06 | — | — | CN | claimed |
| CN-110229165-A | Up-conversion fluorescence probe Rhodamine Derivatives and its application | 苏州科技大学 | 2019-09-13 | — | — | CN | claimed |
| CN-109970751-B | Double-site high-sensitivity pH fluorescent probe and synthesis and application thereof | 济南大学 | 2021-03-02 | — | — | CN | disclosed |
| CN-110229165-B | Up-conversion fluorescent probe rhodamine derivative and application thereof | 苏州科技大学 | 2020-11-06 | — | — | CN | disclosed |
| CN-110229165-B | Up-conversion fluorescent probe rhodamine derivative and application thereof | 苏州科技大学 | 2020-11-06 | — | — | CN | disclosed |
| CN-110229165-A | Up-conversion fluorescence probe Rhodamine Derivatives and its application | 苏州科技大学 | 2019-09-13 | — | — | CN | disclosed |
| CN-108997364-A | The binary channels rhodamine fluorescence probe and its preparation and application of detection mercury ion and iron ion | 东华大学 | 2018-12-14 | — | — | CN | disclosed |
| CN-108191884-A | A kind of synthetic method of more unit and fluorescence unit compound molecules and its application | 湖北工业大学 | 2018-06-22 | — | — | CN | disclosed |
| EP-1499358-B1 | PH-SENSITIVE POLYMER | EVONIK ROEHM GMBH (DE) | 2012-04-18 | — | — | EP | disclosed |
| US-20120014905-A1 | CONUGATED PROTEINS AND PEPTIDES | POLYTHERICS LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| EP-2403538-A1 | CONJUGATED PROTEINS AND PEPTIDES | Polytherics Limited (GB) | 2012-01-11 | — | — | EP | disclosed |
| US-7098030-B2 | Polyampholytes for delivering polyions to a cell | MIRUS BIO CORPORATION (US) | 2006-08-29 | — | — | US | disclosed |
| EP-1620560-A1 | DELIVERY OF SIRNA TO CELLS USING POLYAMPHOLYTES | Mirus Corporation (US) | 2006-02-01 | — | — | EP | disclosed |
| US-20050037496-A1 | Polyampholytes for delivering polyions to a cell | Arrowhead Madison Inc. | 2005-02-17 | — | — | US | disclosed |
| US-6794189-B2 | DRUG DELIVERY; GENE THERAPY | MIRUS BIO CORPORATION | 2004-09-21 | — | — | US | disclosed |
| WO-2004076674-A1 | DELIVERY OF SIRNA TO CELLS USING POLYAMPHOLYTES | MIRUS CORPORATION (US) | 2004-09-10 | — | — | WO | disclosed |
| US-20040162235-A1 | Delivery of siRNA to cells using polyampholytes | MILLIPORE CORPORATION | 2004-08-19 | — | — | US | disclosed |
| US-20020164315-A1 | Polyampholytes for delivering polyions to a cell | Arrowhead Madison Inc. | 2002-11-07 | — | — | US | disclosed |
| US-6383811-B2 | FORMING A COMPLEX OF POLYAMPHOLYTE AND POLYION AND DELIVERING THE COMPLEX INTO A CELL; DRUG DELIVERY | MIRUS CORPORATION | 2002-05-07 | — | — | US | disclosed |
| US-20010024829-A1 | Polyampholytes for delivering polyions to a cell | Arrowhead Madison Inc. | 2001-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120014905-A1 | CONUGATED PROTEINS AND PEPTIDES | C1QBP, CHP1, MAN2A1 | MAPT 4381/4885ALDH1A1 4682/4885RECQL 2222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.