Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 12/20 | 0.48 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.40 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1889325 | 0.89 | PTGDR2 (0.47) | PTGDR2ENPP3ENPP1SRCCCKAR | |
| SCHEMBL2962255 | 0.85 | PTGDR2 (0.46) | PTGDR2ENPP3ENPP1SRCCCKAR | |
| SCHEMBL16208137 | 0.84 | ENPP3 (0.41) | PTGDR2ENPP3ENPP1SRCAGTR1 | |
| SCHEMBL15154929 | 0.83 | PTGDR2 (0.45) | PTGDR2ENPP3ENPP1SRCCCKAR | |
| SCHEMBL2041243 | 0.77 | PTGDR2 (0.41) | PTGDR2ENPP3ENPP1SRC | |
| SCHEMBL13199781 | 0.76 | GAA (0.46) | PTGDR2ENPP3ENPP1CCKAR | |
| SCHEMBL2041118 | 0.75 | PTGDR2 (0.47) | PTGDR2CCKAR | |
| SCHEMBL2043551 | 0.75 | PTGDR2 (0.47) | PTGDR2CCKARPTGDR | |
| SCHEMBL16208220 | 0.75 | AGTR1 (0.42) | PTGDR2ENPP3ENPP1AGTR1 | |
| SCHEMBL7515939 | 0.75 | ENPP3 (0.50) | PTGDR2ENPP3ENPP1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300475-B1 | DIAZACARBAZOLES AND METHODS OF USE | GENENTECH INC (US) | 2014-11-05 | — | — | EP | disclosed |
| WO-2009151598-A1 | DIAZACARBAZOLES AND METHODS OF USE | GENENTECH, INC. (US) | 2009-12-17 | — | — | WO | disclosed |