⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1779488 | 0.72 | — | — | |
| SCHEMBL275888 | 0.72 | — | — | |
| SCHEMBL8086280 | 0.72 | HTR1A (0.41) | — | |
| SCHEMBL24035534 | 0.70 | — | — | |
| SCHEMBL5173532 | 0.70 | — | — | |
| SCHEMBL29290788 | 0.70 | — | — | |
| SCHEMBL17399885 | 0.70 | — | — | |
| SCHEMBL21090338 | 0.68 | HTR1A (0.38) | — | |
| SCHEMBL2011602 | 0.67 | TTR (0.40) | — | |
| SCHEMBL3182180 | 0.67 | TTR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | claimed |
| CN-107903261-A | A kind of synthetic method of 7 azaindole, 3 carboxylic acid | 东莞市联洲知识产权运营管理有限公司 | 2018-04-13 | — | — | CN | disclosed |
| EP-3208269-A1 | INHIBITORS OF C-FMS KINASE | Janssen Pharmaceutica N.V. (BE) | 2017-08-23 | — | — | EP | disclosed |
| US-20090306100-A1 | METHODS OF TREATING SCHIZOPHRENIA | LEXICON PHARMACEUTICALS, INC. | 2009-12-10 | — | — | US | disclosed |
| CN-101252935-A | Pyrrolopyridine, pyrrolopyrimidine and pyrazolopyridine compounds, compositions containing them, and methods of their use | LEXICON GENETICS INC (US) | 2008-08-27 | — | — | CN | disclosed |
| US-20080153811-A1 | methods for treating, managing and preventing cognitive impairment associated with various diseases and disorders, age-associated memory impairment, and dementia. | LEXICON PHARMACEUTICALS, INC. | 2008-06-26 | — | — | US | disclosed |
| US-7297168-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| US-20070049608-A1 | Pyrrolopyridine, pyrrolopyrimidine and pyrazolopyridine compounds, compositions comprising them, and methods of their use | LEXICON PHARMACEUTICALS, INC. | 2007-03-01 | — | — | US | disclosed |
| EP-1737417-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2007-01-03 | — | — | EP | disclosed |
| US-20060258691-A1 | Methods and compositions for improving cognition | LEXICON PHARMACEUTICALS, INC. | 2006-11-16 | — | — | US | disclosed |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | disclosed |
| WO-2005074875-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-08-18 | — | — | WO | disclosed |
| CN-1039079-C | Pesticidal 1-arylpyrroles | RHONE POULENC AGROCHIMIE (FR) | 1998-07-15 | — | — | CN | disclosed |
| CN-1028475-C | Pyrrole insecticides | RHONE POULENC AGROCHIMIE (FR) | 1995-05-24 | — | — | CN | disclosed |
| CN-1057050-A | 1-arylpyrrole insecticidal medicine | RHONE POULENC AGROCHIMIE (FR) | 1991-12-18 | — | — | CN | disclosed |
| CN-1043500-A | PYRROLE INSECTICIDES | RHONE POULENC AGROCHIMIE (FR) | 1990-07-04 | — | — | CN | disclosed |