Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3285074 | 0.75 | — | — | |
| SCHEMBL8086280 | 0.72 | HTR1A (0.41) | HTR1ADRD2DRD4DRD3TSHR | |
| SCHEMBL9019117 | 0.68 | GPR84 (0.45) | HTR1ADRD2DRD4DRD3TSHR | |
| SCHEMBL4397408 | 0.68 | — | — | |
| SCHEMBL7505085 | 0.66 | CYP2A6 (0.32) | — | |
| SCHEMBL1779488 | 0.65 | — | — | |
| SCHEMBL19773472 | 0.64 | HTR1A (0.51) | HTR1ADRD2DRD4DRD3TSHR | |
| SCHEMBL16167007 | 0.64 | GLA (0.47) | — | |
| SCHEMBL15996305 | 0.63 | — | — | |
| SCHEMBL8616508 | 0.62 | LOXL2 (0.48) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019110663-A1 | 1,2,4-OXADIAZOLE DERIVATIVES AS HISTONE DEACETYLASE 6 INHIBITORS | ORYZON GENOMICS, S.A. (ES) | 2019-06-13 | — | — | WO | disclosed |