Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691906 | 1.00 | TSHR (0.61) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL9206028 | 1.00 | TSHR (0.61) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL276911 | 1.00 | TSHR (0.61) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL4399689 | 1.00 | TSHR (0.61) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL7699808 | 1.00 | TSHR (0.61) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL107940 | 1.00 | TSHR (0.61) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL4389498 | 1.00 | TSHR (0.61) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL7697182 | 1.00 | TSHR (0.61) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL95733 | 1.00 | TSHR (0.61) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL277225 | 1.00 | TSHR (0.61) | TSHRTHRBMEN1KMT2ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3380093-B1 | BETA-HYDROXY KETONES AS TOPICAL AGENTS FOR THE PROPHYLAXIS OR TREATMENT OF PHOTODERMATOSES | MERCK PATENT GMBH (DE) | 2021-04-07 | — | — | EP | disclosed |
| US-20200237685-A1 | Beta-Hydroxyketones as topical active ingredients for the prevention or treatment of photodermatoses | MERCK PATENT GMBH (DE) | 2020-07-30 | — | — | US | disclosed |
| US-10660867-B2 | Beta-hydroxyketones as topical active ingredients for the prevention or treatment of photodermatoses | MERCK PATENT GMBH (DE) | 2020-05-26 | — | — | US | disclosed |
| US-20180353442-A1 | Beta-Hydroxyketones as topical active ingredients for the prevention or treatment of photodermatoses | MERCK PATENT GMBH (DE) | 2018-12-13 | — | — | US | disclosed |
| EP-3380093-A1 | BETA-HYDROXY KETONES AS TOPICAL AGENTS FOR THE PROPHYLAXIS OR TREATMENT OF PHOTODERMATOSES | Merck Patent GmbH (DE) | 2018-10-03 | — | — | EP | disclosed |
| WO-2017088950-A1 | BETA-HYDROXY KETONES AS TOPICAL AGENTS FOR THE PROPHYLAXIS OR TREATMENT OF PHOTODERMATOSES | MERCK PATENT GMBH (DE) | 2017-06-01 | — | — | WO | disclosed |
| EP-2508527-B1 | IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND USES THEREOF | SAMSUNG ELECTRONICS CO LTD (KR) | 2015-01-07 | — | — | EP | disclosed |
| EP-2508527-A1 | IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND USE THEREFOR | Showa Denko K.K. (JP) | 2012-10-10 | — | — | EP | disclosed |
| US-20120235132-A1 | IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND USES THEREOF | SAMSUNG ELECTRONICS CO., LTD (KR) | 2012-09-20 | — | — | US | disclosed |
| EP-1385913-B1 | METALLOCENYL PHTHALOCYANINES AS OPTICAL RECORDING MEDIA | BASF SE (DE) | 2009-12-09 | — | — | EP | disclosed |
| WO-2000009522-A1 | METALLOCENYL-PHTHALOCYANINES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-02-24 | — | — | WO | disclosed |
| US-5986042-A | Cross-linked polymer | MITSUI CHEMICALS, INC. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0866084-A2 | Production process of cross-linked polyaspartic acid resin | Mitsui Chemicals, Inc. (JP) | 1998-09-23 | — | — | EP | disclosed |
| EP-0730569-B1 | NOVEL TRIPHENYLENE COMPOUNDS AND PROCESS FOR PRODUCING DISCOIDALLY LIQUID CRYSTALLINE CROSS-LINKED POLYMERS | BASF AG (DE) | 1998-08-26 | — | — | EP | disclosed |
| EP-0856539-A1 | Cross-linked polymer | Mitsui Chemicals, Inc. (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5736068-A | Triphenylene compounds and preparation of discotic liquid crystalline crosslinked polymers | BASF AKTIENGESELLSCHAFT (DE) | 1998-04-07 | — | — | US | disclosed |
| EP-0730569-A1 | NOVEL TRIPHENYLENE COMPOUNDS AND PROCESS FOR PRODUCING DISCOIDALLY LIQUID CRYSTALLINE CROSS-LINKED POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 1996-09-11 | — | — | EP | disclosed |
| WO-1995014652-A1 | NOVEL TRIPHENYLENE COMPOUNDS AND PROCESS FOR PRODUCING DISCOIDALLY LIQUID CRYSTALLINE CROSS-LINKED POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 1995-06-01 | — | — | WO | disclosed |
| US-5214146-A | Color formers for pressure sensitive recording materials | BASF AKTIENGESELLSCHAFT (DE) | 1993-05-25 | — | — | US | disclosed |
| EP-0490200-A1 | Derivatives of quinoline carboxylic acid | BASF Aktiengesellschaft (DE) | 1992-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200237685-A1 | Beta-Hydroxyketones as topical active ingredients for the prevention or treatment of photodermatoses | CYP51A1, HSD17B1, CYP8B1 | TSHR 4867/4885THRB 3193/4885MEN1 4407/4885 |
| US-20120235132-A1 | IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND USES THEREOF | ELP1, AGO2, IPO5 | TSHR 4269/4885THRB 4572/4885MEN1 463/4885 |
| US-10660867-B2 | Beta-hydroxyketones as topical active ingredients for the prevention or treatment of photodermatoses | CYP51A1, HSD17B1, CYP8B1 | TSHR 4867/4885THRB 3193/4885MEN1 4407/4885 |
| US-20180353442-A1 | Beta-Hydroxyketones as topical active ingredients for the prevention or treatment of photodermatoses | CYP51A1, HSD17B1, CYP8B1 | TSHR 4867/4885THRB 3193/4885MEN1 4407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.